Hyperzincaemia in a pet African giant rat (Cricetomys gambianus Waterhouse, 1840) : clinical communication
Journal of the South African Veterinary Association
| Field | Value | |
| Title | Hyperzincaemia in a pet African giant rat (Cricetomys gambianus Waterhouse, 1840) : clinical communication | |
| Creator | Cooper, R.G. Erlwanger, K.H. | |
| Description | Presented is an African giant rat (Cricetomys gambianus) following zinc ingestion. The sick rat was lethargic, withdrawn, had soft, mucus-impregnated faeces and diahorrea, foot twitching and icterus. Comparative age, sex and body weight (b.wt.)-matched analyses were made with a healthy giant rat. Twelve-hourly Urine volume (UV), Haematocrit (Hct), urinary glucose, plasma zinc and Alkaline Phosphatase (ALP) were performed over an 8-week period. Full blood counts were performed and differential WBC counts and microscopic observations were made on blood smears obtained from both healthy and sick rats. Consecutive blood samples were drawn at the end of each week (Weeks 2-6 treatment; Weeks 7-8 post-treatment). Treatment involved oral vitamin B12 supplement at 4 µg / day and 2m diethylenetriaminepentaacetic acid (DTPA) intramuscular injections at 1m / 450g b.wt. / 5 wks (Week 2 - 6). Day 1 showed neutropaenia, Heinz bodies on RBCs (reticulocytes and immature forms). Zinc (Day 1 - end Week 7), glucose (Day 1 - end Week 4), ALP (Day 1 - Week 4) and UV were elevated (Day 1 - end Week 6). Indications of moderate zinc toxicosis following ingestion and stress-associated glucosuria were concluded. | |
| Publisher | AOSIS | |
| Date | 2007-06-04 | |
| Identifier | 10.4102/jsava.v78i3.310 | |
| Source | Journal of the South African Veterinary Association; Vol 78, No 3 (2007); 163-165 2224-9435 1019-9128 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://jsava.co.za/index.php/jsava/article/view/310/293
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