Neuroendocrine tumour in a patient with neurofibromatosis type 1 and HIV
Southern African Journal of HIV Medicine
| Field | Value | |
| Title | Neuroendocrine tumour in a patient with neurofibromatosis type 1 and HIV | |
| Creator | Hiesgen, Juliane Variava, Ebrahim | |
| Description | We report the case of an HIV-positive female patient with neurofibromatosis type 1 who wastreated for recurrent peptic ulcer disease and later developed diabetes mellitus and chronicdiarrhoea. A metastasising somatostatinoma was histologically proven and evidence of aconcomitant gastrin-producing neuroendocrine tumour was found. Neuroendocrine tumours (NETs) are very rare neoplasms originating from a wide variety of endocrine and nervoussystem tissue with the ability to produce different hormones. A somatostatin- and gastrinsecreting NET in a patient with HIV has not been reported in the literature, to the best ofour knowledge. We discuss oncogenic pathomechanisms related to the underlying conditionsand propose stringent monitoring for tumours in HIV-positive patients with phakomatoses aswell as initiation of antiretroviral therapy. | |
| Publisher | AOSIS | |
| Date | 2015-06-26 | |
| Identifier | 10.4102/sajhivmed.v16i1.323 | |
| Source | Southern African Journal of HIV Medicine; Vol 16, No 1 (2015); 4 pages 2078-6751 1608-9693 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajhivmed.org.za/index.php/hivmed/article/view/323/531
https://sajhivmed.org.za/index.php/hivmed/article/view/323/532
https://sajhivmed.org.za/index.php/hivmed/article/view/323/533
https://sajhivmed.org.za/index.php/hivmed/article/view/323/507
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