Tonsil histopathology in HIV-infected versus HIV-uninfected adults
Southern African Journal of HIV Medicine
| Field | Value | |
| Title | Tonsil histopathology in HIV-infected versus HIV-uninfected adults | |
| Creator | Essa, Ridwaan Maharaj, Shivesh Hari, Kapila Motakef, Shahpar | |
| Description | Background: The relationship between HIV and tonsil malignancy has not been fully investigated and established. Both of these diseases prominently feature in the Otorhinolaryngology clinics.Objective: There is minimal data available on the histopathology of tonsillectomy specimens in the HIV-infected population. This retrospective review compared tonsil histopathology between HIV-infected and HIV-uninfected patients.Methods: Of the 319 adult patients undergoing tonsillectomy (01 July 2005 to 30 June 2015), HIV results were available for 160. The histological findings were compared in the HIV-infected and HIV-uninfected subgroups. The effects of age, HIV status and CD4 count on the risk of malignancy were determined.Results: There were 86 patients who were HIV-infected and 74 were uninfected. Reactive lymphoid hyperplasia was the most common diagnosis in both groups (77%). Malignancies were diagnosed in eight HIV-infected and six HIV-uninfected patients, an insignificant difference.Conclusion: The majority of patients undergoing tonsillectomy had benign conditions. HIV status does not appear to be a specific risk factor for tonsil malignancies, but advanced age may be. | |
| Publisher | AOSIS | |
| Date | 2019-05-28 | |
| Identifier | 10.4102/sajhivmed.v20i1.936 | |
| Source | Southern African Journal of HIV Medicine; Vol 20, No 1 (2019); 5 pages 2078-6751 1608-9693 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajhivmed.org.za/index.php/hivmed/article/view/936/1427
https://sajhivmed.org.za/index.php/hivmed/article/view/936/1426
https://sajhivmed.org.za/index.php/hivmed/article/view/936/1428
https://sajhivmed.org.za/index.php/hivmed/article/view/936/1425
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