Successful treatment of bilateral visual loss caused by HIV-associated optic neuritis
Southern African Journal of HIV Medicine
| Field | Value | |
| Title | Successful treatment of bilateral visual loss caused by HIV-associated optic neuritis | |
| Creator | Cullen, Claire Matlala, Baile Laher, Fatima Pienaar, Ané | |
| Description | Optic neuritis is not an uncommon diagnosis in HIV-infected patients, but it is rarely idiopathic. We report a case of a young HIV-infected woman who developed optic neuritis as her presenting manifestation of HIV infection. She had initially experienced sudden-onset right-sided painful visual loss; the left eye had become involved within days. Bilateral swollen discs were apparent on fundoscopy. Investigations were performed for meningitis (including bacterial, cryptococcal, tuberculous and syphilitic types), auto-immune diseases, toxoplasma, rubella, cytomegalovirus, viral hepatitis, HTLV-1/2, HIV-1/2 and syphilis. The only positive result was a reactive HIV enzyme-linked immunosorbent assay. The CD4 count was 85 cells/µl. A post-contrast magnetic resonance imaging scan of the brain illustrated enhancement of the optic nerves. Treatment was 3 days of intravenous methylprednisolone 1 g daily, followed by 11 days of oral prednisone 60 mg daily. Highly active antiretroviral therapy was initiated after 2 weeks. Vision improved from day 6 after commencement of steroid therapy, with ongoing recovery at 5 months. | |
| Publisher | AOSIS | |
| Date | 2011-12-01 | |
| Identifier | 10.4102/sajhivmed.v12i4.169 | |
| Source | Southern African Journal of HIV Medicine; Vol 12, No 4 (2011); 29 2078-6751 1608-9693 | |
| Language | eng | |
| Relation |
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https://sajhivmed.org.za/index.php/hivmed/article/view/169/284
https://sajhivmed.org.za/index.php/hivmed/article/view/169/283
https://sajhivmed.org.za/index.php/hivmed/article/downloadSuppFile/169/90
https://sajhivmed.org.za/index.php/hivmed/article/downloadSuppFile/169/91
https://sajhivmed.org.za/index.php/hivmed/article/downloadSuppFile/169/92
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