A case of emmonsiosis in an HIV-infected child

Southern African Journal of HIV Medicine

Field Value
Title A case of emmonsiosis in an HIV-infected child
Creator Lochan, Harsha Naicker, Preneshni Maphanga, Tsidiso Ryan, Anthea Pillay, Komala Govender, Nelesh P. Eley, Brian
Subject Medicine, Paediatric Infectious Diseases HIV, Paediatrics, Opportunistic infection
Description Opportunistic fungal infections can cause significant morbidity and mortality in immunocompromised patients. We describe a paediatric case of an unusual disseminated fungal infection. A three-year-old HIV-infected child with severe immunosuppression (CD4+ T-cell count 12 × 106 /L) was admitted to hospital with pneumonia, gastroenteritis and herpes gingivostomatitis. Despite antibacterial and antiviral therapy, he experienced high fevers and developed an erythematous maculopapular rash and abdominal tenderness. The child’s condition progressively worsened during the admission. A thermally dimorphic fungus was cultured from bone marrow and identified as an Emmonsia species on DNA sequencing. The patient made a good recovery on amphotericin B deoxycholate and antiretroviral therapy. Itraconazole was continued for a minimum of 12 months, allowing for immune reconstitution to occur. This case is the first documented description of disseminated disease caused by a novel Emmonsia species in an HIV-infected child in South Africa.
Publisher AOSIS
Date 2015-06-11
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Case report
Format text/html application/octet-stream text/xml application/pdf
Identifier 10.4102/sajhivmed.v16i1.352
Source Southern African Journal of HIV Medicine; Vol 16, No 1 (2015); 4 pages 2078-6751 1608-9693
Language eng
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajhivmed.org.za/index.php/hivmed/article/view/352/528 https://sajhivmed.org.za/index.php/hivmed/article/view/352/529 https://sajhivmed.org.za/index.php/hivmed/article/view/352/530 https://sajhivmed.org.za/index.php/hivmed/article/view/352/495
Coverage South Africa — —
Rights Copyright (c) 2015 Harsha Lochan, Preneshni Naicker, Tsidiso Maphanga, Anthea Ryan, Komala Pillay, Nelesh P. Govender, Brian Eley https://creativecommons.org/licenses/by/4.0