Native valve endocarditis due to Candida parapsilosis in an adult patient
Southern African Journal of HIV Medicine
| Field | Value | |
| Title | Native valve endocarditis due to Candida parapsilosis in an adult patient | |
| Creator | Moodley, Krishnee Govind, Chetna Narsai Peer, Abdool Kader Cassim Dawood, Shabbir Hassim, Mohamed Hanif Deonarain, Julian | |
| Description | Candida endocarditis is rare, but associated with a high mortality. The most common species implicated is Candida albicans. The epidemiology of invasive Candida infections is changing, with a predominance of non-albicans species causing invasive disease. We describe a case of Candida parapsilosis endocarditis in an HIV-positive patient with pre-existing mitral valve disease and renal failure on haemodialysis. The patient presented with fever and malaise. Clinical examination revealed pulmonary oedema and severe mitral regurgitation. Blood cultures were positive for C. parapsilosis. β-D-glucan assay levels were elevated. An echocardiogram showed large, friable vegetations on the mitral valve. C. parapsilosis was cultured from the haemodialysis tip and the vegetations. The patient responded well to mitral valve replacement and antifungal therapy. A high index of suspicion and aggressive diagnostic modalities and therapy are essential in patients with candidaemia, to decrease mortality due to this condition. | |
| Publisher | AOSIS | |
| Date | 2013-09-17 | |
| Identifier | 10.4102/sajhivmed.v14i3.68 | |
| Source | Southern African Journal of HIV Medicine; Vol 14, No 3 (2013); 138-140 2078-6751 1608-9693 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajhivmed.org.za/index.php/hivmed/article/view/68/103
https://sajhivmed.org.za/index.php/hivmed/article/view/68/102
https://sajhivmed.org.za/index.php/hivmed/article/downloadSuppFile/68/22
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