A review of pharmacological therapy for glaucoma

African Vision and Eye Health

Field Value
Title A review of pharmacological therapy for glaucoma
Creator Mathebula, S.D.
Subject — Glaucoma, intraocular pressure, optic nerve, visual field, anti-glaucoma medications
Description Glaucoma is a chronic or acute disease in which optic nerve damage occurs in a characteristic way. In  primary  open  angle  glaucoma  (POAG),  the manifestations of the optic nerve damage include visible excavation that develops in the optic nerve head and regions of the retina lose ability to detect all the elements that go into the total sensory prod-uct called vision.1, 2  When these regions worsen and enlarge to coalesce, the result is blindness.The intraocular pressure (IOP) has a causative role in producing the damage. All eyes have an in-ternal pressure to keep them inflated, perhaps 17 mmHg on the average, ± 5 mmHg standard devia-tion. In at least two thirds of the eyes that suffer glaucomatous damage, the intraocular pressure is high, at least a bit above the pressure found in 95% of the non-glaucomatous population. The cut-off is in the region of 20 to 22 mmHg used by most definitions.2 However, a normal or even low intra-ocular pressure can be harmful to some eyes, and when it is, the person has normal or low tension glaucoma. The traditional treatment of glaucoma has logically been to lower the intraocular pres-sure, to prevent further damage to the optic nerve, though previous damage is not undone.
Publisher AOSIS
Date 2005-12-19
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format application/pdf
Identifier 10.4102/aveh.v64i3.227
Source African Vision and Eye Health; South African Optometrist: Vol 64, No 3 (2005); 89-96 2410-1516 2413-3183
Language eng
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Rights Copyright (c) 2005 S.D. Mathebula https://creativecommons.org/licenses/by/4.0