The effect of an angiotensin-converting enzyme inhibitor on water and electrolyte balance in water-restricted sheep
Journal of the South African Veterinary Association
| Field | Value | |
| Title | The effect of an angiotensin-converting enzyme inhibitor on water and electrolyte balance in water-restricted sheep | |
| Creator | Meintjies, R.A. Engelbrecht, H. | |
| Description | The importance of angiotensin II in the regulation of water and electrolyte balance in sheep is questionable. In this trial the effects of an angiotensin-converting enzyme (ACE) inhibitor were quantified in sheep on restricted water intake. Comparing the phase of water restriction only with that of water restriction plus ACE inhibition, significant increases were observed during the latter phase in urine volume, sodium and potassium excretion via the urine, sodium concentration in the plasma and osmolar clearance. Urine osmolarity decreased with inhibition of angiotensin II formation while variables such as water, sodium and potassium loss via the faeces were unaffected. Most of the renal effects of ACE inhibition, except the increase in urinary potassium excretion, were explicable in terms of the established functions of angiotensin II. Furthermore, results of this trial indicate that angiotensin II has no significant effect on the intestine in regulating water and electrolyte excretion via the faeces. | |
| Publisher | AOSIS | |
| Date | 1999-07-12 | |
| Identifier | 10.4102/jsava.v70i4.783 | |
| Source | Journal of the South African Veterinary Association; Vol 70, No 4 (1999); 147-150 2224-9435 1019-9128 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://jsava.co.za/index.php/jsava/article/view/783/756
|
|
ADVERTISEMENT
