Molecular characterisation of Babesia gibsoni infection from a Pit-bull terrier pup recently imported into South Africa
Journal of the South African Veterinary Association
| Field | Value | |
| Title | Molecular characterisation of Babesia gibsoni infection from a Pit-bull terrier pup recently imported into South Africa | |
| Creator | Matjila, P.T. Penzhorn, B.L. Leisewitz, A.L. Bhoora, R. Barker, R. | |
| Description | Canine babesiosis caused by Babesia gibsoni was diagnosed in a 3-month-old Pit-bull pup during a routine clinical examination. Diagnosis was confirmed by way of smear examination, PCR, Reverse Line Blot (RLB) and sequence analysis which showed 100% homology with B. gibsoni (Japan AB118032) and Babesia sp. (Oklahoma) (AF205636). Haematology showed moderate anaemia and severe thrombocytopenia. Treatment was initiated with diminazene aceturate (Berenil RTU(R) followed by 2 doses of imidocarb diproprionate (Forray-65(R) 3 days and 14 days later, respectively. Babesia gibsoni DNA was still detectable 2 weeks post-treatment on the PCR/RLB test. A 10-day course of combination drug therapy using atovaquone and azithromycin was initiated. Blood samples taken on Day 1 and Day 40 after completion of treatment were negative for B. gibsoni DNA on PCR/RLB test. The implications of a possible introduction of B. gibsoni into South Africa are discussed. | |
| Publisher | AOSIS | |
| Date | 2007-05-31 | |
| Identifier | 10.4102/jsava.v78i1.277 | |
| Source | Journal of the South African Veterinary Association; Vol 78, No 1 (2007); 2-5 2224-9435 1019-9128 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://jsava.co.za/index.php/jsava/article/view/277/261
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