Effect of packing on changes in erythrocyte osmotic fragility and malondialdehyde concentration in donkeys administered with ascorbic acid
Onderstepoort Journal of Veterinary Research
Field | Value | |
Title | Effect of packing on changes in erythrocyte osmotic fragility and malondialdehyde concentration in donkeys administered with ascorbic acid | |
Creator | Olaifa, Folashade Ayo, Joseph O. Ambali, Suleiman F. Rekwot, Peter I. | |
Description | Experiments were performed with the aim of investigating the effect of packing on erythrocyte osmotic fragility (EOF) and malondialdehyde (MDA) concentration in donkeys, and the effect of ascorbic acid (AA). Twelve apparently healthy donkeys raised under the traditional extensive system served as experimental subjects. Six donkeys administered orally with AA (200 mg/kg) and subjected to packing were used as experimental animals, whilst six others not administered with AA served as controls. Blood samples were collected pre- and post-packing from all the donkeys for the determination of MDA and EOF. At 0.3% Sodium Chloride (NaCl) concentration, the percentage haemolysis was 93.69% ± 2.21% in the control donkeys and the value was significantly (P 0.05) higher than the value of 71.31% ± 8.33%, recorded in the experimental donkeys. The post-packing MDA concentration obtained in the control donkeys was 39.62 µmol ± 4.16 µmol, and was not significantly different (P 0.05) from the value of 35.97 µmol ± 2.88 µmol recorded in the experimental donkeys. In conclusion, the increase in haemolysis obtained in the donkeys suggested that packing induced oxidative stress, which was ameliorated by AA administration. | |
Publisher | AOSIS | |
Date | 2012-12-05 | |
Identifier | 10.4102/ojvr.v79i1.413 | |
Source | Onderstepoort Journal of Veterinary Research; Vol 79, No 1 (2012); 5 pages 2219-0635 0030-2465 | |
Language | eng | |
Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://ojvr.org/index.php/ojvr/article/view/413/745
https://ojvr.org/index.php/ojvr/article/view/413/746
https://ojvr.org/index.php/ojvr/article/view/413/747
https://ojvr.org/index.php/ojvr/article/view/413/744
|
|
ADVERTISEMENT