Histomorphometrical and ultrastructural study of the effects of carbendazim on the magnum of the Japanese quail (Coturnix coturnix japonica)

Onderstepoort Journal of Veterinary Research

 
 
Field Value
 
Title Histomorphometrical and ultrastructural study of the effects of carbendazim on the magnum of the Japanese quail (Coturnix coturnix japonica)
 
Creator Kimaro, Wahabu H. Madekurozwa, Mary-Catherine Groenewald, Herman B.
 
Subject Anatomy; female reproductive biology; toxicology carbendazim; magnum; morphometry; ultrastructure; Japanese quail
Description The study investigated the effect of various doses of carbendazim on the morphology of the magnum of the Japanese quail. No morphological changes were observed in the magnum in birds treated with carbendazim at doses of 25 mg/kg and 100 mg/kg bodyweight. A carbendazim dose of 400 mg/kg bodyweight was the lowest dose which caused morphological changes in the magnum. Histologically, carbendazim caused pyknosis and glandular atrophy in the magnum mucosa. Carbendazim also caused significant decreases in the height of the mucosal folds, epithelial height, glandular width and glandular luminal diameter at 400 mg/kg and 800 mg/kg (p 0.05). At ultrastructural level, dose-dependent deciliation was observed. Pyknotic nuclei, dilated cisternae of rough endoplasmic reticulum, swollen mitochondria, numerous vacuoles and lysosomes in the luminal and glandular epithelia were identified. The observed degenerative changes could be due to cytoskeletal disruption caused by carbendazim toxicity. Degeneration of the luminal and glandular cells in the magnum pose a potential threat to the egg production and reproduction of exposed birds.
 
Publisher AOSIS
 
Contributor Deutscher Akademischer Aus-tauschdienst (DAAD) University of Pretoria (UP) South African Veterinary Foundation (SAVF)
Date 2013-07-19
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Experimental
Format text/html application/octet-stream text/xml application/pdf
Identifier 10.4102/ojvr.v80i1.579
 
Source Onderstepoort Journal of Veterinary Research; Vol 80, No 1 (2013); 8 pages 2219-0635 0030-2465
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://ojvr.org/index.php/ojvr/article/view/579/864 https://ojvr.org/index.php/ojvr/article/view/579/865 https://ojvr.org/index.php/ojvr/article/view/579/866 https://ojvr.org/index.php/ojvr/article/view/579/863
 
Coverage — — Avian species
Rights Copyright (c) 2013 Wahabu H. Kimaro, Mary-Catherine Madekurozwa, Herman B. Groenewald https://creativecommons.org/licenses/by-nd/4.0
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