Immunohistochemical studies of the enteric nervous system and interstitial cells of Cajal in the canine stomach
Onderstepoort Journal of Veterinary Research
| Field | Value | |
| Title | Immunohistochemical studies of the enteric nervous system and interstitial cells of Cajal in the canine stomach | |
| Creator | Musara, Colin Vaillant, Camille | |
| Description | The distribution of interstitial cells of Cajal (ICC), the probable pacemakers in gastrointestinal motility, was investigated using an antigenic marker of gastric ICC known as C-Kit. Antiserum raised against the general neuronal marker protein gene peptide 9.5 (PGP) as well as the nitrergic neuronal marker neuronal nitric oxide synthase (nNOS) were used to investigate the distribution of gastric nerves. Polyclonal goat anti-human C-Kit was reliable in labelling ICC in the stomach. Two classes of ICC were identified according to their distribution: ICC-MY distributed around the periphery of myenteric ganglia and ICC-IM in the circular and longitudinal muscle layers. The neuronal marker PGP was reliably consistent in revealing the density and distribution of the enteric nervous system. Density of nerve fibres was higher in circular smooth muscle than in longitudinal smooth muscle. From nNOS immunohistochemistry, it is evident that inhibitory (nitrergic) nerves constitute a substantial fraction of the enteric nervous system. | |
| Publisher | AOSIS | |
| Date | 2013-03-05 | |
| Identifier | 10.4102/ojvr.v80i1.518 | |
| Source | Onderstepoort Journal of Veterinary Research; Vol 80, No 1 (2013); 4 pages 2219-0635 0030-2465 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://ojvr.org/index.php/ojvr/article/view/518/792
https://ojvr.org/index.php/ojvr/article/view/518/793
https://ojvr.org/index.php/ojvr/article/view/518/794
https://ojvr.org/index.php/ojvr/article/view/518/791
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