Blueprint for building a biorepository in a resource-limited setting that follows international best practices
African Journal of Laboratory Medicine
| Field | Value | |
| Title | Blueprint for building a biorepository in a resource-limited setting that follows international best practices | |
| Creator | Abimiku, Alash'le G. Croxton, Talishea Ozumba, Petronilla J. Agala, Ndidi Balogun, Olasinbo Jonathan, Emmanuel Onyemata, Enzenwa Ndifon, Kachimi Nadoma, Sunji Anazodo, Thankgod Peters, Sam Beiswanger, Christine M. | |
| Description | ackground:Genetic diversity is abundant on the African continent. However, genomic research has been hampered by a lack of high quality and extensively annotated biospecimens and the necessary infrastructure to support such a technology-intensive effort.Objective: The Institute of Human Virology Nigeria (IHVN) partnered with the H3Africa Consortium and the Coriell Institute for Medical Research to build an internationally recognised biorepository for the receipt, processing, storage and distribution of biospecimens for biomedical research. Here, the authors describe the procedures, challenges and results encountered.Results: Key requirements for a high-quality biorepository were identified: (1) institutional support of infrastructure and services, (2) on-site trained staff with primary commitment to the biorepository, (3) reliance on best practices from globally recognised biorepository groups, (4) early implementation of a quality management system, (5) adoption of a laboratory information management system with demonstrated versatility in functions, (6) collaboration with external experts and sharing of experience through abstracts, newsletters, published manuscripts, and attendance at meetings and workshops, (7) strict adherence to local and national ethical standards and (8) a sustainability plan that is reviewed and updated annually.Conclusion: Utilising published best practices of globally recognised experts in the biorepository field as a benchmark, IHVN expanded and reorganised its existing laboratory facility and staff to take on this new purpose. | |
| Publisher | AOSIS | |
| Date | 2019-08-28 | |
| Identifier | 10.4102/ajlm.v8i1.722 | |
| Source | African Journal of Laboratory Medicine; Vol 8, No 1 (2019); 12 pages 2225-2010 2225-2002 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://ajlmonline.org/index.php/ajlm/article/view/722/1339
https://ajlmonline.org/index.php/ajlm/article/view/722/1338
https://ajlmonline.org/index.php/ajlm/article/view/722/1340
https://ajlmonline.org/index.php/ajlm/article/view/722/1337
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