Serum canine pancreatic-specific lipase concentrations in dogs with naturally occurring Babesia rossi infection
Journal of the South African Veterinary Association
| Field | Value | |
| Title | Serum canine pancreatic-specific lipase concentrations in dogs with naturally occurring Babesia rossi infection | |
| Creator | Köster, Liza S. Steiner, Jörg M. Suchodolski, Jan S. Schoeman, Johan P. | |
| Description | Babesia rossi is the cause of a highly virulent multisystemic disease with a variable outcome, which is a reliable model of systemic inflammatory response syndrome (SIRS). The objective of this study was to determine the concentration of canine pancreatic-specific lipase (cPL) in a population of dogs with naturally acquired B. rossi infection. In addition, the associations between serum cPL and death and SIRS status were examined. An observational study recruited 87 dogs diagnosed with B. rossi infection and serum cPL concentrations were measured daily until discharge or death. The median concentration of serum cPL was 124.0 µg/L (interquartile range: 51.0 µg/L – 475.5 µg/L) on admission (n = 87) and 145.5 µg/L (62.3 µg/L – 434.0 µg/L) on day two of hospitalisation (n = 40). Twenty-four dogs (28%) had a serum cPL concentration within the diagnostic range for pancreatitis ( 400 µg/L) at admission with 13 dogs (32.5%) presenting as such on the second day of hospitalisation. The median concentration of serum cPL in dogs with SIRS was 158 µg/L (interquartile range: 52.5 µg/L – 571.5 µg/L; n = 53), which was significantly higher than in those without SIRS (75 µg/L; 50.3 µg/L – 131.8 µg/L; n = 32) (P = 0.018). This study demonstrated that an unexpectedly high number of dogs diagnosed with naturally acquired canine babesiosis had a serum cPL concentration within the diagnostic range for acute pancreatitis and a significantly higher serum cPL concentration was found in dogs that were classified as having SIRS. | |
| Publisher | AOSIS | |
| Date | 2015-08-13 | |
| Identifier | 10.4102/jsava.v86i1.1297 | |
| Source | Journal of the South African Veterinary Association; Vol 86, No 1 (2015); 7 pages 2224-9435 1019-9128 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://jsava.co.za/index.php/jsava/article/view/1297/1692
https://jsava.co.za/index.php/jsava/article/view/1297/1693
https://jsava.co.za/index.php/jsava/article/view/1297/1694
https://jsava.co.za/index.php/jsava/article/view/1297/1680
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