Mother-to-child transmission of HIV and its predictors among HIV-exposed infants at Bamenda Regional Hospital, Cameroon

African Journal of Laboratory Medicine

Field Value
Title Mother-to-child transmission of HIV and its predictors among HIV-exposed infants at Bamenda Regional Hospital, Cameroon
Creator Fondoh, Victor N. Mom, Njong A.
Subject Public Health Mother-to-child; HIV Transmission; HIV exposed infants; PMTCT interventions
Description Background: Mother-to-child transmission (MTCT) of HIV, has been a major global public health burden. Despite the use of antiretroviral prophylaxis by HIV-positive pregnant women and their infants, safe obstetric practice and safe infant feeding habits in the prevention of MTCT of HIV, the prevalence of HIV among HIV-exposed infants is still high in Cameroon.Objective: Our objectives were to determine the prevalence, assess the predictors and determine the effect of combination antiretroviral therapy (cART) on MTCT of HIV at the regional hospital in Bamenda, Cameroon.Methods: This was a retrospective study. Secondary data from 877 HIV-exposed infants aged ≤ 72 weeks were extracted from the records between January 2008 and December 2014. The predictors and effect of cART on MTCT of HIV were analysed using a multivariable logistic regression model and risk analysis, respectively.Results: Out of 877 HIV-exposed infants, 62 were positive for HIV, giving a prevalence of 7.1%. Maternal antiretroviral intervention and infant age group were statistically significant predictors of MTCT of HIV. HIV-positive mothers who were on cART were 2.49 times less likely to transmit HIV than those who were not on cART.Conclusion: In order to reduce the prevalence of HIV among HIV-exposed infants, maternal antiretroviral intervention should be targeted and the use of cART by HIV-positive pregnant women should be encouraged.
Publisher AOSIS
Date 2017-12-14
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Retrospective study; Secondary data, Logistic Regression Analysis
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ajlm.v6i1.589
Source African Journal of Laboratory Medicine; Vol 6, No 1 (2017); 7 pages 2225-2010 2225-2002
Language eng
Coverage — — Age group; Gender; Mother ARVs intervention; Child ARVs intervention; Obstetric intervention; Infant Feeding intervention
Rights Copyright (c) 2017 Victor N. Fondoh, Njong A. Mom