Whole genome sequencing for drug resistance determination in Mycobacterium tuberculosis
African Journal of Laboratory Medicine
| Field | Value | |
| Title | Whole genome sequencing for drug resistance determination in Mycobacterium tuberculosis | |
| Creator | Omar, Shaheed V. Joseph, Lavania Said, Halima M. Ismail, Farzana Ismail, Nabila Gwala, Thabisile L. Ismail, Nazir A. | |
| Description | South Africa remains challenged with a high tuberculosis burden accompanied by an increase in drug resistant cases. We assessed the use of the Illumina MiSeq, a next-generation sequencing platform for whole genome sequencing, followed by bioinformatic analysis using a commercial software package to determine resistance to selected drugs used for Mycobacterium tuberculosis treatment in our setting. Whole genome sequencing shows potential as a diagnostic platform for the detection of drug resistance in Mycobacterium tuberculosis with the provision of information for several drugs simultaneously. | |
| Publisher | AOSIS | |
| Date | 2019-02-21 | |
| Identifier | 10.4102/ajlm.v8i1.801 | |
| Source | African Journal of Laboratory Medicine; Vol 8, No 1 (2019); 5 pages 2225-2010 2225-2002 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://ajlmonline.org/index.php/ajlm/article/view/801/1251
https://ajlmonline.org/index.php/ajlm/article/view/801/1250
https://ajlmonline.org/index.php/ajlm/article/view/801/1252
https://ajlmonline.org/index.php/ajlm/article/view/801/1249
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