Trends in leprosy case detection in Rwanda, 1995–2011: analysis of 17 years of laboratory data

African Journal of Laboratory Medicine

 
 
Field Value
 
Title Trends in leprosy case detection in Rwanda, 1995–2011: analysis of 17 years of laboratory data
 
Creator Uwimana, Innocent Bizimungu, Nestor Ingabire, Fabrice Mukamukwiye, Elyse Sharangabo, Odette Ngabonziza, Semuto C. Kamanzi, Eliane
 
Subject — Leprosy; Hansen bacilli; Prevalence rate (PR); Case detection rate (CDR); Ziehl Neelsen (ZN)
Description Background: Leprosy, or Hansen’s disease, is a chronic, infectious disease caused by Mycobacterium leprae. It remains one of the leading causes of deformity and physical disability.Objective: We analysed laboratory records to assess trends in prevalence rates and case detection rates (CDRs) in Rwanda. Methods: A retrospective review of detected leprosy cases from the records of the Rwanda National Reference Laboratory over a 17-year period (1995–2011) was conducted. Skin biopsy samples were analysed microscopically using Ziehl-Neelsen staining technique to identify M. leprae.Results: Cumulatively, 266 suspected cases were reported between 1995 and 2011. Of the suspected cases, 77 (28.9%) were laboratory confirmed as having leprosy. Among detected cases, 59 (76.6%) were men and 18 (23.4%) women. The male:female ratio was 3:1. There were 77 registered leprosy cases over the 17-year period of the study, and the prevalence rate was 0.005 per 10 000 population. A gradual decrease in the prevalence rate was observed from 0.015 per 10 000 population in 2003 to 0.003 per 10 000 population in 2010. From 1995 to 2011, the CDR did not exceed one per 10 000 population.Conclusion: This laboratory review demonstrates a declining trend in prevalence rates and CDR during the period of the study. Early case detection and a sustainable leprosy control programme remain the cornerstones of reducing the physical and socio-economic burden of leprosy in Rwanda.
 
Publisher AOSIS
 
Contributor
Date 2017-02-28
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ajlm.v6i1.426
 
Source African Journal of Laboratory Medicine; Vol 6, No 1 (2017); 4 pages 2225-2010 2225-2002
 
Language eng
 
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https://ajlmonline.org/index.php/ajlm/article/view/426/744 https://ajlmonline.org/index.php/ajlm/article/view/426/743 https://ajlmonline.org/index.php/ajlm/article/view/426/745 https://ajlmonline.org/index.php/ajlm/article/view/426/737
 
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Rights Copyright (c) 2017 Innocent Uwimana, Nestor Bizimungu, Fabrice Ingabire, Elyse Mukamukwiye, Odette Sharangabo, Semuto C. Ngabonziza, Eliane Kamanzi https://creativecommons.org/licenses/by/4.0
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