Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals

Journal of the South African Veterinary Association

 
 
Field Value
 
Title Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals
 
Creator Brown, Lara J. Brown, Geoff Kydd, Julia Stout, Tom A.E. Schulman, Martin L.
 
Subject — equines; equid herpesvirus type 1 and 4; placentae; foetal membranes; foals; qPCR; latency; Thoroughbred
Description Equid herpesvirus type 1 is primarily a respiratory tract virus associated with poor athletic performance that can also cause late gestation abortion, neonatal foal death and encephalomyelopathy. Horizontal transmission is well described, whereas evidence of vertical transmission of equid herpesvirus type 1 associated with the birth of a healthy foal has not been demonstrated. This study sampled a population of Thoroughbred mares (n = 71), and their healthy neonatal foals and foetal membranes, to test for the presence of both equid herpesvirus types 1 and 4 using a quantitative polymerase chain reaction assay. Foetal membrane swabs and tissue samples were taken immediately post-partum, and venous blood samples and nasal swabs were obtained from both mare and foal 8 h after birth. Neither equid herpesvirus type 1 nor equid herpesvirus type 4 nucleic acid was detected in any sample, and it was concluded that there was no active shedding of equid herpesvirus types 1 and 4 at the time of sampling. Consequently, no evidence of vertical transmission of these viruses could be found on this stud farm during the sampling period.
 
Publisher AOSIS
 
Contributor Wits Health Consortium
Date 2019-05-30
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip application/xml application/pdf
Identifier 10.4102/jsava.v90i0.1736
 
Source Journal of the South African Veterinary Association; Vol 90 (2019); 5 pages 2224-9435 1019-9128
 
Language eng
 
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https://jsava.co.za/index.php/jsava/article/view/1736/2385 https://jsava.co.za/index.php/jsava/article/view/1736/2384 https://jsava.co.za/index.php/jsava/article/view/1736/2386 https://jsava.co.za/index.php/jsava/article/view/1736/2383
 
Coverage — — —
Rights Copyright (c) 2019 Lara J. Brown, Geoff Brown, Julia Kydd, Tom A.E. Stout, Martin L. Schulman https://creativecommons.org/licenses/by/4.0
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