Immunohistochemical study of a canine neurofibroma

Journal of the South African Veterinary Association

 
 
Field Value
 
Title Immunohistochemical study of a canine neurofibroma
 
Creator Fattahian, Hamidreza Mortazavi, Pejman Moosavian, Hamidreza Mohyeddin, Hamid Moridpour, Roozbeh
 
Subject — dog; immunohistochemistry; neurofibroma; S-100; vimentin
Description Accurate diagnostic approaches to differentiate peripheral nerve sheet tumours from others have not been firmly established. The aim of this case report was to diagnose neurofibroma using a combination of diagnostic imaging, histopathology and immunohistochemistry, which were applied to a canine neurofibroma arising in the left mandible. The tumour was surgically excised and examined histologically. Round or spindle cells, with elongated, dense and homogenous chromatin and pale cytoplasm typical of Schwann cells in an abundant fibromyxomatous stroma, with ruby collagen fibres were seen. Immunohistochemistry demonstrated that S-100 and vimentin were more than 70% positive. Neurofibroma may therefore be recognisable using markers such as S-100 and vimentin.
 
Publisher AOSIS
 
Contributor —
Date 2012-08-07
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/jsava.v83i1.18
 
Source Journal of the South African Veterinary Association; Vol 83, No 1 (2012); 4 pages 2224-9435 1019-9128
 
Language eng
 
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Rights Copyright (c) 2012 Hamidreza Fattahian, Pejman Mortazavi, Hamidreza Moosavian, Hamid Mohyeddin, Roozbeh Moridpour https://creativecommons.org/licenses/by/4.0
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