Record Details

The breed prevalence of Dog Erythrocyte Antigen 1.1 in the Onderstepoort area of South Africa and its significance in selection of canine blood donors

Journal of the South African Veterinary Association

Field Value
Title The breed prevalence of Dog Erythrocyte Antigen 1.1 in the Onderstepoort area of South Africa and its significance in selection of canine blood donors
Creator Van der Merwe, L.L. Jacobson, L.S. Pretorius, J.G.
Subject — Blood Donors; Blood Transfusion; Blood Typing; Breed Prevalence; Canine; DEA1.1; Dog; Dog Erythrocyte Antigen; Haemolysis
Description The blood group antigen Dog Erythrocyte Antigen (DEA) 1.1 is clinically the most important canine blood group as DEA 1.1 antibodies are capable of causing acute haemolytic, potentially life-threatening transfusion reactions. Dogs do not have naturally occurring antibodies to DEA 1.1 but are rapidly sensitised by the first incompatible transfusion. The prevalence of DEA 1.1 in the general dog population is estimated at 42-46 %. Canine blood donors registered with the Onderstepoort Animal Blood Bank (n = 93) as well as potential donors (n = 140) were typed for DEA 1.1 using a monoclonal antibody card kit. All dogs came from the Onderstepoort area, near Pretoria, Gauteng province, South Africa. Overall prevalence of DEA 1.1 was 47 %. Prevalence was 47 % in purebred dogs and 48 % in mongrels. Distinct breed differences were noted with less than 20 % of German shepherd dogs and Boxers and greater than 75 % of Rottweilers, Great Danes, St Bernards and Dalmations testing DEA 1.1 positive. Knowledge of local breed differences will increase effectiveness of blood donor recruitment.
Publisher AOSIS Publishing
Date 2002-07-06
Type — —
Format application/pdf
Identifier 10.4102/jsava.v73i2.555
Source Journal of the South African Veterinary Association; Vol 73, No 2 (2002); 53-56
Language en
Coverage — — —
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