Record Details

Serial haematology results in transfused and non-transfused dogs naturally infected with Babesia rossi

Journal of the South African Veterinary Association


 
 
Field Value
 
Title Serial haematology results in transfused and non-transfused dogs naturally infected with Babesia rossi
 
Creator Scheepers, E.; Department of Companion Animal Clinical Studies,
Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, Pretoria, 0110 South Africa. Leisewitz, A. L.; Department of Companion Animal Clinical Studies,
Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, Pretoria, 0110 South Africa. Thompson, P. N.; Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, Pretoria, 0110 South Africa. Christopher, M. M.; Department of Pathology, Microbiology & Immunology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA, USA.
 
Subject — —
Description This prospective longitudinal study investigated the progression of haematological changes in 32 transfused and 54 non-transfused dogs naturally infected with Babesia rossi over the 1st 6 days following diagnosis and treatment. The effect of patient age on the results of complete blood counts was determined. Haematology data were analysed at presentation and at 24 hours, 3 days and 6 days after presentation. Dogs were treated with diminazene aceturate at diagnosis and a blood transfusion was given if deemed clinically required. Mildly to moderately regenerative normocytic normochromic anaemia was observed in all dogs throughout the study period. Transfused dogs more often had an inflammatory leukogram at presentation and at 24 hours, than dogs that were not transfused. In dogs with a left shift, a concurrent normal or decreased segmented neutrophil count was found more commonly than neutrophilia. Severe thrombocytopenia that resolved within a week was common. Blood transfusion alleviated the anaemia, but had no significant effect on white blood cell or platelet responses. Blood cell responses were not significantly influenced by age. In conclusion, the red blood cell and white blood cell responses were less than expected in dogs with babesiosis, given the degree of anaemia and inflammation present. The magnitude of thrombocytopenia and rapid return of the platelet count to normal suggested a possible immune-mediated mechanism for the thrombocytopenia.
 
Publisher AOSIS Publishing
 
Contributor
Date 2011-04-13
 
Type — —
Format application/pdf
Identifier 10.4102/jsava.v82i3.51
 
Source Journal of the South African Veterinary Association; Vol 82, No 3 (2011); 136-143
 
Language en
 
Coverage — — —
Rights Copyright information Ownership of copyright in terms of the Work remains with the authors. The authors retain the non-exclusive right to do anything they wish with the Work, provided attribution is given to the place and detail of original publication, as set out in the official citation of the Work published in the journal. The retained right specifically includes the right to post the Work on the authors’ or their institutions’ websites or institutional repository. Disclaimer: The publisher, editors and title owner accept no responsibility for any statement made or opinion expressed by any other person in this Work. Consequently, they will not be liable for any loss or damage sustained by any reader as a result of his or her action upon any statement or opinion in this Work. In cases where a manuscript is NOT accepted for publication by the editorial board, the portions of this agreement regarding the publishing licensing shall be null and void and the authors will be free to submit this manuscript to any other publication for first publication. Our copyright policies are author-friendly and protect the rights of our authors and publishing partners.