Record Details

Comparative evaluation of halothane anaesthesia in medetomidine–butorphanol and midazolam–butorphanol premedicated water buffaloes (Bubalus bubalis)

Journal of the South African Veterinary Association


 
 
Field Value
 
Title Comparative evaluation of halothane anaesthesia in medetomidine–butorphanol and midazolam–butorphanol premedicated water buffaloes (Bubalus bubalis)
 
Creator Malik, V.; aDepartment of Surgery, College of Veterinary Sciences and Animal Husbandry, DeenDayal Upadhayaya Veterinary and Animal Science University, Mathura, Uttar Pradesh, 281001, India. Kinjavdekar, P.; Division of Surgery, Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India. Amarpal, Amarpal; Division of Surgery, Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India. Aithal, H. P.; Division of Surgery, Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India. Pawde, A. M.; Division of Surgery, Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India. Surbhi, Surbhi; Division of Surgery, Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, 243122, India.
 
Subject — —
Description Six clinically healthy male water buffaloes (Bubalus bubalis) 2–3 years of age and weighing 290–325 kg were used for 2 different treatments (H1 andH2). The animals of groupH1 were premedicated with medetomidine (2.5 g/kg, i.v.) and butorphanol (0.05 mg/kg, i.v.), while in groupH2 midazolam (0.25 mg/kg) and butorphanol (0.05 mg/kg) were used intravenously. Induction of anaesthesia was achieved by 5%thiopental sodium inH1 (3.85±0.63 mg/kg) and H2 (6.96 ± 0.45 mg/kg) groups. The anaesthesia was maintained with halothane in 100 % oxygen through a large animal anaesthetic machine. Better analgesia and sedation with a significantly lower dose of thiopental for induction and significantly higher values of sternal recumbency time and standing time were recorded in group H1 than in group H2 , whereas no significant (P > 0.05) difference for the halothane concentration was observed between groups H1 and H2. Significant decrease in heart rate was observed in group H1 whereas it significantly increased in group H2. In both groups, RR decreased during the preanaesthetic period, which increased significantly (P<0.01) after halothane administration. In both groups a significant (P<0.01) fall in RT was recorded from 20 min to the end of observation period. A significant (P < 0.05) fall in MAP was observed in group H1 from 15 min until the end, while in group H2 MAP increased nonsignificantly (P > 0.05) after premedication and a significant (P<0.05) occurredafter thiopental administration. In both groups a significant (P<0.01) increase in CVP and a significant (P<0.01) decrease in SpO2 were observed after premedication which persisted up to 120 min. ECG changes included significant (P<0.01) decrease and increase in QRS amplitudes in groupsH1 andH2 respectively, a significant (P < 0.05) increase in PR interval was recorded at 15 min in group H1, a significant (P<0.05) decrease in PR interval in groupH2 , a significant (P<0.05) decrease in T wave amplitude in groupH1, and a significant (P<0.01) increase in duration of T wave in groupH1 . It is concluded that both combinations can be used safely in buffaloes for surgery of 2 h duration but better sedation, analgesia and muscular relaxation and more dose sparing effect on anaesthetics and shorter recovery times were observed in group H1.
 
Publisher AOSIS Publishing
 
Contributor
Date 2011-04-13
 
Type — —
Format application/pdf
Identifier 10.4102/jsava.v82i1.28
 
Source Journal of the South African Veterinary Association; Vol 82, No 1 (2011); 8-17
 
Language en
 
Coverage — — —
Rights Copyright information Ownership of copyright in terms of the Work remains with the authors. The authors retain the non-exclusive right to do anything they wish with the Work, provided attribution is given to the place and detail of original publication, as set out in the official citation of the Work published in the journal. The retained right specifically includes the right to post the Work on the authors’ or their institutions’ websites or institutional repository. Disclaimer: The publisher, editors and title owner accept no responsibility for any statement made or opinion expressed by any other person in this Work. Consequently, they will not be liable for any loss or damage sustained by any reader as a result of his or her action upon any statement or opinion in this Work. In cases where a manuscript is NOT accepted for publication by the editorial board, the portions of this agreement regarding the publishing licensing shall be null and void and the authors will be free to submit this manuscript to any other publication for first publication. Our copyright policies are author-friendly and protect the rights of our authors and publishing partners.