Clinical remission of Crohn’s disease symptoms following the adoption of therapeutic carbohydrate reduction: A retrospective single case report

Journal of Metabolic Health (previously Journal of Insulin Resistance)

 
 
Field Value
 
Title Clinical remission of Crohn’s disease symptoms following the adoption of therapeutic carbohydrate reduction: A retrospective single case report
 
Creator Walker, Henry M. Tidman, Melanie M. White, Dawn R. White, Timothy A.
 
Subject Crohn's disease; ulcerative colitis; inflammatory bowel disease; low-carb diet; ketogenic diet; Symptoms remission; inflammatory bowel disease Crohn’s disease; ulcerative colitis; inflammatory bowel disease; low-carb diet; ketogenic diet; symptom remission; inflammatory bowel disease; therapeutic carbohydrate reduction.
Description Low-carbohydrate dietary approaches are increasingly explored as adjunctive strategies for Crohn’s disease (CD), particularly in patients who experience limitations or adverse effects with standard biologic therapies. Dietary intervention (DI) may offer a non-pharmacological option to support symptom control and remission. Evidence remains limited, particularly at the individual clinical level. This single-patient, retrospective case report describes an adult with established CD who initiated a therapeutic carbohydrate-restricted diet under clinical guidance. The intervention was implemented as part of ongoing disease management and followed longitudinally during routine care. Clinical outcomes were assessed through symptom patterns, medication use, and sustained follow-up over an extended observation period. Following initiation of the carbohydrate-restricted dietary approach, the patient achieved remission of gastrointestinal symptoms and progressively discontinued pharmacologic therapy. Symptom recurrence was temporally associated with lapses in dietary adherence and resolved promptly upon resumption of the intervention. Sustained adherence was related to continued symptom control and medication independence throughout follow-up. This case suggests that therapeutic carbohydrate reduction may support remission and medication discontinuation in select individuals with CD. The findings underscore the need for controlled clinical trials to evaluate the safety, durability and generalisability of DIs in inflammatory bowel disease. Dietary strategies may represent a complementary avenue for individualised disease management.
 
Publisher AOSIS
 
Contributor —
Date 2026-03-18
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Case Report of an Interventional study
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/jmh.v9i1.134
 
Source Journal of Metabolic Health; Vol 9, No 1 (2026); 7 pages 2960-0391 3105-4323
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://journalofmetabolichealth.org/index.php/jmh/article/view/134/444 https://journalofmetabolichealth.org/index.php/jmh/article/view/134/445 https://journalofmetabolichealth.org/index.php/jmh/article/view/134/446 https://journalofmetabolichealth.org/index.php/jmh/article/view/134/447
 
Coverage — — 33 year old, male
Rights Copyright (c) 2026 Henry C. Walker, Melanie M. Tidman, Dawn R. White, Timothy A. White https://creativecommons.org/licenses/by/4.0
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