Perioperative care of an infant with pyruvate dehydrogenase deficiency

Southern African Journal of Anaesthesia and Analgesia

 
 
Field Value
 
Title Perioperative care of an infant with pyruvate dehydrogenase deficiency
 
Creator Dewhirst, Elisabeth Tobias, Joseph D Rehman, Saif
 
Subject regional anesthesia; paediatric anaesthesia pyruvate dehydrogenase complex deficiency; metabolic disorder; carbohydrate metabolims
Description The authors present the anaesthetic management of two infants with pyruvate dehydrogenase complex deficiency (PDCD), a rare genetic disorder of carbohydrate metabolism leading to lactic acidosis and neurological impairment. In the first case, a seven-month-old infant, undergoing closed reduction of a dislocated hip, received general anaesthesia with a volatile agent. In the second case, spinal anaesthesia was administered to a six-month-old infant undergoing Achilles tendon lengthening. There were no adverse outcomes in both cases. Key components of perioperative care included minimising perioperative stress, and avoiding exacerbation of the lactic acidosis. Previous reports regarding the perioperative care of such patients are reviewed, and recommendations for anaesthetic care discussed.
 
Publisher AOSIS
 
Contributor
Date 2012-03-01
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article case report
Format application/pdf
Identifier 10.1080/22201173.2012.10872837
 
Source Southern African Journal of Anaesthesia and Analgesia; Vol 18, No 2 (2012); 115-118 2220-1173 2220-1181
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajaa.co.za/index.php/sajaa/article/view/563/557 https://sajaa.co.za/index.php/sajaa/article/downloadSuppFile/563/165
 
Coverage United States 2011 Two infants with PCD deficiency
Rights Copyright (c) 2011 Elisabeth Dewhirst, Joseph D Tobias, Saif Rehman https://creativecommons.org/licenses/by/4.0
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