Psychotropic prescribing patterns during pregnancy in two South African mental health clinics

Journal of the Colleges of Medicine of South Africa

 
 
Field Value
 
Title Psychotropic prescribing patterns during pregnancy in two South African mental health clinics
 
Creator Farmer, Catherine du Toit, Elsa Botha, Ulla Niehaus, Dana Koen, Liezl
 
Subject Psychiatry; maternal mental health psychotropics; pregnancy; polypharmacy; maternal mental health; prescription patterns; psychiatric diagnosis
Description Background: Given that there is a significant burden of mental illness during pregnancy, psychotropic polypharmacy during this period is commonly found in clinical practice. In South Africa, however, there is a paucity of data on the use of psychotropics during pregnancy.Methods: This was a retrospective descriptive study of 303 pregnant women attending two specialised maternal mental health clinics from presentation to six weeks postpartum. Demographic data, psychiatric history, medical comorbidity, pregnancy-related, and prescription data were collected and tabulated at treatment-as-usual visits. Polypharmacy prevalence was defined as the prescription of two or more psychotropics for at least 90 days.Results: A majority of the study group was diagnosed with major depressive disorder (n = 161, 53.1%), and non-tricyclic antidepressants were the most prescribed medication class (n = 195, 64.4%). One-third of the participants received prescriptions in all three trimesters. Polypharmacy criteria were met in 18.8% (n = 57) of the sample population.Conclusion: The prescription patterns in the study sample appeared to be in line with current international protocols. Prescribing psychotropics during pregnancy remains challenging because of the need to weigh up the potential risks of medication-related effects on the mother and baby against those of discontinuing treatment.Contribution: This study may raise awareness and assist medical professionals regarding the rational use of psychotropic medication during pregnancy.
 
Publisher AOSIS
 
Contributor
Date 2025-10-17
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Retrospective descriptive study
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/jcmsa.v3i1.188
 
Source Journal of the Colleges of Medicine of South Africa; Vol 3, No 1 (2025); 9 pages 2960-110X 3105-4331
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://jcmsa.org.za/index.php/jcmsa/article/view/188/780 https://jcmsa.org.za/index.php/jcmsa/article/view/188/781 https://jcmsa.org.za/index.php/jcmsa/article/view/188/782 https://jcmsa.org.za/index.php/jcmsa/article/view/188/783
 
Coverage Africa; South Africa; Western Cape; Cape Town April 2011 - May 2016 Age; marital status; highest level of education; pregnancy related factors; psychiatric diagnoses; prescriptions
Rights Copyright (c) 2025 Catherine Farmer, Elsa du Toit, Ulla Botha, Dana Niehaus, Liezl Koen https://creativecommons.org/licenses/by/4.0
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