Six-month trajectory of physical function in ICU survivors: Experience from an Eastern Cape centre

South African Journal of Physiotherapy

 
 
Field Value
 
Title Six-month trajectory of physical function in ICU survivors: Experience from an Eastern Cape centre
 
Creator van der Merwe, Elizabeth Stroud, Louise Sharp, Gary van Vuuren, Noline Paruk, Fathima
 
Subject Medicine; critical care critical care; physical impairment; ICU-acquired weakness; Medical Research Council score; six-minute walk test; health-related quality of life; post ICU pain; post ICU syndrome
Description Background: Physical impairment affects up to 60% of intensive care unit (ICU) survivors due to factors such as ICU-acquired neuromuscular weakness (ICU-AW), chronic pain, deconditioning and reduced organ and metabolic function. This impairment is linked to lower health-related quality of life (HRQOL).
Objectives: Our study aimed to assess physical impairment and HRQOL among critically ill patients post hospital discharge.
Method: Intensive care unit survivors were assessed six weeks and six months post hospital discharge. Physical performance was evaluated using the six-minute walk test (6MWT) and muscle strength with the Medical Research Council (MRC) score. Patients’ HRQOL was determined using the Rand Short Form-36 questionnaire.
Results: A total of 107 patients (median age 42 years), including 50% with COVID-19, completed the 6-month follow-up. Although significant improvements were observed, 53.5% walked less than 80% of the predicted 6MWT distance at six months, with females disproportionately affected. Poor physical performance was associated with lower physical and mental HRQOL. Pain interfering with activities was reported by 26.2% at six months. Only 2% met full criteria for ICU-AW at six months. By six weeks, only 15% had attended physiotherapy.
Conclusion: Intensive care unit survivors exhibited a high incidence of physical impairment and pain at six months, impacting HRQOL. Very few patients met full ICU-AW criteria.
Clinical implications: Physical impairment after critical illness is multifactorial and is not only attributable to muscle weakness. The recovery process of young, previously non-frail ICU survivors in the public healthcare setting may be improved by introducing rehabilitation pathways.
 
Publisher AOSIS
 
Contributor Kidney, Infectious Diseases and Crtical Care Non Profit Company
Date 2025-08-12
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Prospective cohort
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajp.v81i1.2228
 
Source South African Journal of Physiotherapy; Vol 81, No 1 (2025); 10 pages 2410-8219 0379-6175
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajp.co.za/index.php/sajp/article/view/2228/3971 https://sajp.co.za/index.php/sajp/article/view/2228/3972 https://sajp.co.za/index.php/sajp/article/view/2228/3973 https://sajp.co.za/index.php/sajp/article/view/2228/3974
 
Coverage Eastern Cape; South Africa — ICU survivors
Rights Copyright (c) 2025 Elizabeth van der Merwe, Louise Stroud, Gary Sharp, Noline van Vuuren, Fathima Paruk https://creativecommons.org/licenses/by/4.0
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