Iron supplementation in children to prevent deficiency and anaemia: A qualitative synthesis

African Journal of Primary Health Care & Family Medicine

 
 
Field Value
 
Title Iron supplementation in children to prevent deficiency and anaemia: A qualitative synthesis
 
Creator Mabetha, Denny Kallon, Idriss I. Visser, Marianne Naude, Celeste Odendaal, Willem Brand, Amanda S. Cooper, Sara
 
Subject Public health; qualitative research; review; child and maternal health acceptability; anaemia; children; equity; feasibility; low and middle-income countries; iron-deficiency anaemia; qualitative evidence synthesis
Description Background: Iron deficiency anaemia in young children is a major problem globally, particularly in low- and middle-income countries (LMICs). The World Health Organization (WHO) recommends preventive oral iron supplements to reduce the prevalence of iron deficiency and anaemia in high-prevalence settings.Aim: To conduct a qualitative evidence synthesis exploring the factors influencing the acceptability, feasibility and equity of preventive oral iron supplementation in young children for the Global Evidence, Local Adaptation (GELA) project, which supports the development of evidence-informed, locally relevant guideline recommendations in three sub-Saharan countries.Method: We searched MEDLINE, Epistemonikos, CINAHL and PsycInfo from inception to 07 July 2023 for eligible studies. We synthesised the data using thematic analysis and assessed the methodological quality of the studies (using an adaptation of the Critical Appraisal Skills Programme tool) and confidence in the review findings (using GRADE-CERQual).Results: We included six studies, five from LMICs. Findings indicated knowledge and perceptions about iron supplementation, as well as relationships with intervention providers, can have a beneficial or detrimental influence on caregiver acceptance (moderate to high confidence); caregiver acceptance may be negatively affected by a lack of reliable information but can potentially be enhanced through community-based education (moderate confidence); healthcare workers’ knowledge, resources and support may improve the feasibility of intervention provision (moderate confidence) and socio-economic challenges around access to the intervention may adversely affect equity (low confidence).Conclusion: A complex interplay of contextual factors may impact the provision and uptake of preventive oral iron supplementation in young children.Contribution: This work provides insights into how preventative oral iron supplementation might be contextually tailored.
 
Publisher AOSIS
 
Contributor GELA project EDCTP2 programme supported by the European Union Research, Evidence and Development Initiative (READ-It)
Date 2025-05-14
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Review of qualitative studies
Format text/html application/epub+zip text/xml application/pdf application/pdf
Identifier 10.4102/phcfm.v17i1.4825
 
Source African Journal of Primary Health Care & Family Medicine; Vol 17, No 1 (2025); 14 pages 2071-2936 2071-2928
 
Language eng
 
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The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://phcfm.org/index.php/phcfm/article/view/4825/8228 https://phcfm.org/index.php/phcfm/article/view/4825/8229 https://phcfm.org/index.php/phcfm/article/view/4825/8230 https://phcfm.org/index.php/phcfm/article/view/4825/8232 https://phcfm.org/index.php/phcfm/article/view/4825/8231
 
Coverage Global Studies up until 7 July 2023 N/A
Rights Copyright (c) 2025 Denny Mabetha, Idriss I. Kallon, Marianne Visser, Celeste Naude, Willem Odendaal, Amanda S. Brand, Sara Cooper https://creativecommons.org/licenses/by/4.0
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