Audit of failure rate of Coartem to treat falciparum malaria at single fourteen day follow up
South African Family Practice
| Field | Value | |
| Title | Audit of failure rate of Coartem to treat falciparum malaria at single fourteen day follow up | |
| Creator | Vaughan Williams, C.H. La Cock, C. Henry, G.F.J. Ross, A.J. | |
| Description | Objective: To assess the failure rate of the new first line treatment regime for uncomplicated falciparum malaria in KwaZulu-Natal of Coartem tablets (20mg aftemether and 120mg lumefantrine - Novartis South Africa (PTY Ltd.Design: A before-after study.Setting: Ndumo Clinic, Ingwavuma District, Kwazulu-Natal, South Africa, February 2001.Study Group: 67 patients presenting to Ndumo clinic with uncomplicated malaria, diagnosed by symptoms and positive immunochromographic test for plasmodium falciparum.Main outcome measures: All 58 follow-up slides obtained were negative. 8 patients failed to return, and 1 slide washed off. Only 43 smears were positive at day 0 of which 36 had follow-up smears.Conclusions: No resistance to Coartem was shown at day 4, and Coartem has been shown to be more effective at clearing falciparum malaria parasites than a previous regime of sulfadoxine/pyrimethamine with chlorine. | |
| Publisher | AOSIS | |
| Date | 2002-03-30 | |
| Identifier | 10.4102/safp.v25i3.2055 | |
| Source | South African Family Practice; Vol 25, No 3 (2002); 5 2078-6204 2078-6190 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://safpj.co.za/index.php/safpj/article/view/2055/2609
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