Investigating methylparaben’s oxidative stress effects on rainbow trout blood, liver, and kidney toxicity
Onderstepoort Journal of Veterinary Research
| Field | Value | |
| Title | Investigating methylparaben’s oxidative stress effects on rainbow trout blood, liver, and kidney toxicity | |
| Creator | Calisir, Mert Nur, Gokhan Caylak, Emrah | |
| Description | The widespread use of parabens has led to their accumulation in aquatic environments. This study examined the effects of methylparaben on rainbow trout, dividing 96 fish into control and treatment groups (1 mg/L, 5 mg/L, and 8 mg/L). Results showed dose-dependent weight loss, altered hepatosomatic indices, increased serum urea, uric acid, and Malondialdehyde (MDA) levels, and decreased Glutathione Peroxidase (GSH-Px) activity. Histopathological analysis revealed liver and kidney abnormalities in treated groups, including hepatocyte degeneration, proliferation in the bile duct, glomerular atrophy, reduced haematopoietic tissue, increased melanomacrophage centres, necrosis and fibrosis.Contribution: These findings highlight methylparaben’s toxic effects, emphasising the need for stricter regulations and further research to safeguard aquatic ecosystems and understand its impact on aquatic organisms. | |
| Publisher | AOSIS | |
| Date | 2025-03-07 | |
| Identifier | 10.4102/ojvr.v92i1.2200 | |
| Source | Onderstepoort Journal of Veterinary Research; Vol 92, No 1 (2025); 7 pages 2219-0635 0030-2465 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://ojvr.org/index.php/ojvr/article/view/2200/2710
https://ojvr.org/index.php/ojvr/article/view/2200/2711
https://ojvr.org/index.php/ojvr/article/view/2200/2712
https://ojvr.org/index.php/ojvr/article/view/2200/2713
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