Minor salivary gland tumours: Malignant or benign? A 10-year local retrospective review

Journal of the Colleges of Medicine of South Africa

 
 
Field Value
 
Title Minor salivary gland tumours: Malignant or benign? A 10-year local retrospective review
 
Creator Grobbelaar, Johan Wright, Kathryne E. Thomas, Ann Adam, Shaun E.
 
Subject Otorhinolaryngology; Ear, nose and throat; Cancer; Salivary glands minor salivary gland tumours; salivary gland tumours; malignant; benign; pleomorphic adenoma, polymorphous adenocarcinoma.
Description Background: This study reports on our local incidence of minor salivary gland tumours (MSGT).Methods: This was a retrospective descriptive study including all patients with MSGT treated at Tygerberg Hospital from 2015 to 2024.Results: Benign and malignant tumours’ incidence was almost equal at 46.46% and 53.54%, respectively (N = 99). Pleomorphic adenomas were the most common tumour overall (38.38%) and the most common benign tumour. Polymorphous low-grade adenocarcinoma (PLGA) was the most common malignant tumour (15.15%). The palate was the most common site. Primary sites other than lips and palate had a 93.23% malignant incidence. Benign tumours occurred statistically significantly in younger patients than malignant tumours (p  0.001) (42.74 years versus 56.02 years).Conclusion: We did not see the high malignant incidence that is frequently reported in otorhinolaryngology textbooks. Pleomorphic adenomas remain the most common and occur most commonly in the palate. We did show an unusually high incidence of PLGA. Primary sites other than palate and lips should raise the suspicion of malignant MSGT.Contribution: The study highlights the importance of reporting on local data because disease patterns may vary greatly based on genetic and geographical differences. Further investigation is needed to explain possible local factors contributing to the high incidence of PLGA.
 
Publisher AOSIS
 
Contributor None
Date 2025-02-17
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Retrospective descriptive
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/jcmsa.v3i1.126
 
Source Journal of the Colleges of Medicine of South Africa; Vol 3, No 1 (2025); 4 pages 2960-110X 3105-4331
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://jcmsa.org.za/index.php/jcmsa/article/view/126/441 https://jcmsa.org.za/index.php/jcmsa/article/view/126/442 https://jcmsa.org.za/index.php/jcmsa/article/view/126/443 https://jcmsa.org.za/index.php/jcmsa/article/view/126/444
 
Coverage South Africa; Western Cape 2015-2024 Age; Gender; Malignant; Benign
Rights Copyright (c) 2025 Johan Grobbelaar, Kathryne E. Wright, Ann Thomas, Shaun E. Adam https://creativecommons.org/licenses/by/4.0
ADVERTISEMENT