Viral load non-suppression among adolescents and youth living with HIV in South Africa

Southern African Journal of Infectious Diseases

 
 
Field Value
 
Title Viral load non-suppression among adolescents and youth living with HIV in South Africa
 
Creator Molopa, Lesiba O. Ginyana, Thembelihle P. Vondo, Noloyiso Magobo, Rindidzani Maseko, Goitseone Zungu, Nompumelelo Zuma, Khangelani Simbayi, Leickness Mabaso, Musawenkosi Moyo, Sizulu
 
Subject HIV Epidemiology HIV; antiretroviral treatment; viral load; non-suppression; adolescent; youth; South Africa
Description Background: Despite the increased initiation and uptake of antiretroviral therapy (ART) in South Africa, some people living with HIV (PLHIV) who are on ART still have non-suppressed viral load (VL).Objectives: This study aimed to determine the prevalence of VL non-suppression among adolescents and youth (aged 12 years – 24 years) living with HIV and on ART in South Africa, as well as the factors associated with it.Method: Data from the 2017 South African national HIV prevalence, incidence, behaviour, and communication survey were analysed. The survey used a multistage-stratified cluster sampling design. A backward stepwise multivariable generalised linear model was used to identify factors associated with VL non-suppression.Results: The study included 340 participants aged 12 years – 24 years, with a median age of 21 (interquartile range [IQR]: 18–23). The proportion of adolescents and youth living with HIV and on ART with non-suppressed VL was 19.2% (95% confidence interval [CI]: 14.4–25.3). Approximately 60% of the participants were not on ART. The odds of VL non-suppression were significantly higher among youth aged 15 years – 19 years (adjusted odds ratio [AOR] = 1.63 [95% CI: 1.24–2.13], p = 0.001) and aged 20 years – 24 years (AOR = 1.22 [95% CI: 1.06–1.41], p = 0.005) compared to adolescents aged 12 years – 14 years. The odds were significantly lower among individuals of other races (AOR = 0.80 [95% CI: 0.69–0.92], p = 0.003) compared to black African people.Conclusion: Findings suggest a need for ART education and counselling as part of treatment support. In addition, the promotion of HIV awareness as part of strengthening the HIV treatment and prevention cascade.Contribution: The article showed the prevalence of VL non-suppression and associated factors among adolescents and youth.
 
Publisher AOSIS Publishing
 
Contributor
Date 2024-09-25
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Cross-sectional
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajid.v39i1.629
 
Source Southern African Journal of Infectious Diseases; Vol 39, No 1 (2024); 6 pages 2313-1810 2312-0053
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajid.co.za/index.php/sajid/article/view/629/1580 https://sajid.co.za/index.php/sajid/article/view/629/1581 https://sajid.co.za/index.php/sajid/article/view/629/1582 https://sajid.co.za/index.php/sajid/article/view/629/1583
 
Coverage — — 12-24 years; Male and Female; Black African and other
Rights Copyright (c) 2024 Lesiba O. Molopa, Thembelihle P. Ginyana, Noloyiso Vondo, Rindidzani Magobo, Goitseone Maseko, Nompumelelo Zungu, Khangelani Zuma, Leickness Simbayi, Musawenkosi Mabaso, Sizulu Moyo https://creativecommons.org/licenses/by/4.0
ADVERTISEMENT