Newly implemented community CD4 service in Tshwaragano, Northern Cape province, South Africa, positively impacts result turn-around time

African Journal of Laboratory Medicine

 
 
Field Value
 
Title Newly implemented community CD4 service in Tshwaragano, Northern Cape province, South Africa, positively impacts result turn-around time
 
Creator Coetzee, Lindi-Marie Cassim, Naseem Glencross, Deborah K.
 
Subject Immunology; HIV; operational science CD4 testing; district laboratory; turn-around-time; immunology; HIV; operational science
Description Background: The Northern Cape is South Africa’s largest province with an HIV prevalence of 7.1% versus a 13.5% national prevalence. CD4 testing is provided at three of five National Health Laboratory Service district laboratories, each covering a 250 km precinct radius. Districts without a local service report prolonged CD4 turn-around times (TAT).Objective: This study documented the impact of a new CD4 laboratory in Tshwaragano in the remote John Taolo Gaetsewe district of the Northern Cape, South Africa.Methods: CD4 test volumes and TAT (total, pre-analytical, analytical, and post-analytical) data for the Northern Cape province were extracted for June 2018 to October 2019. The percentage of CD4 results within the stipulated 40-h TAT cut-off and the median and 75th percentiles of all TAT parameters were calculated. Pre-implementation, samples collected at Tshwaragano were referred to Kimberley or Upington, Northern Cape, South Africa.Results: Pre-implementation, 95.4% of samples at Tshwaragano were referred to Kimberley for CD4 testing (36.3% of Kimberley’s test volumes). Only 7.5% of Tshwaragano’s total samples were referred post-implementation. The Tshwaragano laboratory’s CD4 median total TAT decreased from 24.7 h pre-implementation to 12 h post-implementation (p = 0.003), with 95.0% of results reported within 40 h. The Kimberley laboratory workload decreased by 29.0%, and testing time significantly decreased from 10 h to 4.3 h.Conclusion: The new Tshwaragano CD4 service significantly decreased local TAT. Upgrading existing community laboratories to include CD4 testing can alleviate provincial service load and improve local access, TAT and efficiency in the centralised reference laboratory.
 
Publisher AOSIS
 
Contributor No financial support for this study
Date 2022-06-03
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — retrospective data analysis
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ajlm.v11i1.1376
 
Source African Journal of Laboratory Medicine; Vol 11, No 1 (2022); 9 pages 2225-2010 2225-2002
 
Language eng
 
Relation
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https://ajlmonline.org/index.php/ajlm/article/view/1376/2246 https://ajlmonline.org/index.php/ajlm/article/view/1376/2247 https://ajlmonline.org/index.php/ajlm/article/view/1376/2248 https://ajlmonline.org/index.php/ajlm/article/view/1376/2249
 
Coverage Northern Cape province; South Africa NA time and date stamps during sample processing from sample taken to result reviewed
Rights Copyright (c) 2022 Lindi-Marie Coetzee, Naseem Cassim, Deborah K. Glencross https://creativecommons.org/licenses/by/4.0
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