Retrospective analysis of Vitek®2 performance compared to manual broth micro-dilution for colistin susceptibility testing of Acinetobacter baumanniicomplex isolates in South Africa

African Journal of Laboratory Medicine

 
 
Field Value
 
Title Retrospective analysis of Vitek®2 performance compared to manual broth micro-dilution for colistin susceptibility testing of Acinetobacter baumanniicomplex isolates in South Africa
 
Creator Fadana, Vuyolwethu Thomas, Teena von Knorring, Nina
 
Subject Pathology; microbiology Acinetobacter; colistin; broth micro-dilution; Vitek®2; antimicrobial susceptibility testing
Description The manual broth micro-dilution (mBMD) is the recommended reference method for colistin minimum inhibitory concentration determination; however, it is not as readily available in South Africa as the Vitek®2. This retrospective study compared the performance of Vitek®2 against mBMD in determining the colistin minimum inhibitory concentration of 337 extensively drug-resistant Acinetobacter baumannii complex isolates. Vitek®2 yielded a categorical agreement of 89%, an essential agreement of 56%, a major error rate of 8% and a very major error rate of 55%. The Vitek®2 is not an alternative to mBMD for colistin susceptibility testing.
 
Publisher AOSIS
 
Contributor Charlotte Maxeke Johannesburg Academic Hospital University of Witwatersrand National Health Laboratory Services
Date 2022-02-28
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Retrospective analysis
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ajlm.v11i1.1597
 
Source African Journal of Laboratory Medicine; Vol 11, No 1 (2022); 4 pages 2225-2010 2225-2002
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://ajlmonline.org/index.php/ajlm/article/view/1597/2136 https://ajlmonline.org/index.php/ajlm/article/view/1597/2137 https://ajlmonline.org/index.php/ajlm/article/view/1597/2138 https://ajlmonline.org/index.php/ajlm/article/view/1597/2139
 
Coverage Sub-Saharan Africa Modern inpatient
Rights Copyright (c) 2022 Vuyolwethu Fadana, Teena Thomas, Nina von Knorring https://creativecommons.org/licenses/by/4.0
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