Cross-validation of a high-performance liquid chromatography nevirapine plasma assay in a resource-limited setting in Zimbabwe
African Journal of Laboratory Medicine
| Field | Value | |
| Title | Cross-validation of a high-performance liquid chromatography nevirapine plasma assay in a resource-limited setting in Zimbabwe | |
| Creator | Makita-Chingombe, Faithful Podany, Anthony T. Mykris, Timothy Muzambi, Farai Browne, Richard W. Ocque, Andrew J. DiFrancesco, Robin Winchester, Lee C. Fletcher, Courtney V. Mudzviti, Tinashe Maponga, Charles C. Morse, Gene D. | |
| Description | An international HIV pharmacology specialty laboratory (PSL) was established at the University of Zimbabwe to increase bioanalytical and investigator capacities. Quantitation of plasma nevirapine in samples from the AIDS Clinical Trials Group protocol 5279 was compared between the University of Nebraska Medical Center PSL and the University of Zimbabwe PSL. Both PSLs employed internally developed methods utilising reverse-phase high-performance liquid chromatography with ultraviolet detection. Eighty-seven percent of the cross-validation results exhibited ± 20% difference. | |
| Publisher | AOSIS | |
| Date | 2021-07-08 | |
| Identifier | 10.4102/ajlm.v10i1.1264 | |
| Source | African Journal of Laboratory Medicine; Vol 10, No 1 (2021); 5 pages 2225-2010 2225-2002 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://ajlmonline.org/index.php/ajlm/article/view/1264/1983
https://ajlmonline.org/index.php/ajlm/article/view/1264/1985
https://ajlmonline.org/index.php/ajlm/article/view/1264/1986
https://ajlmonline.org/index.php/ajlm/article/view/1264/1987
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