Carriage of colistin-resistant Gram-negative bacteria in children from communities in Cape Town (Tuberculosis child multidrug-resistant preventive therapy trial sub-study)

Southern African Journal of Infectious Diseases

 
 
Field Value
 
Title Carriage of colistin-resistant Gram-negative bacteria in children from communities in Cape Town (Tuberculosis child multidrug-resistant preventive therapy trial sub-study)
 
Creator Snyman, Yolandi Whitelaw, Andrew C. Maloba, Motlatji R.B. Hesseling, Anneke C. Newton-Foot, Mae
 
Subject antibiotic resistance; medical microbiology; bacteriology colistin resistance; Enterobacterales; children; healthy; communities; Cape Town; South Africa.
Description Colistin is a last-resort antibiotic against multidrug-resistant, Gram-negative bacteria. Colistin resistance has been described in the clinical settings in South Africa. However, information on carriage of these bacteria in communities is limited. This study investigated gastrointestinal carriage of colistin-resistant Escherichia coli and Klebsiella spp. and mcr genes in children from communities in Cape Town. Colistin-resistant E. coli was isolated from two participants (4%, 2/50), and mcr-1-mcr-9 genes were not detected. Gastrointestinal carriage of colistin-resistant Enterobacterales was rare; however, continuous extensive surveillance is necessary to determine the extent of carriage and its contribution to resistance observed in clinical settings.
 
Publisher AOSIS Publishing
 
Contributor National Research Foundation of South Africa NHLS Research Trust
Date 2021-02-23
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Descriptive study
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajid.v36i1.241
 
Source Southern African Journal of Infectious Diseases; Vol 36, No 1 (2021); 4 pages 2313-1810 2312-0053
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajid.co.za/index.php/sajid/article/view/241/550 https://sajid.co.za/index.php/sajid/article/view/241/549 https://sajid.co.za/index.php/sajid/article/view/241/551 https://sajid.co.za/index.php/sajid/article/view/241/548
 
Coverage Cape Town; South Africa — children
Rights Copyright (c) 2021 Yolandi Snyman, Andrew C. Whitelaw, Motlatji R.B. Maloba, Anneke C. Hesseling, Mae Newton-Foot https://creativecommons.org/licenses/by/4.0
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