Haematological reference intervals for healthy adults in Bamenda, Cameroon

African Journal of Laboratory Medicine

Field Value
Title Haematological reference intervals for healthy adults in Bamenda, Cameroon
Creator Fondoh, Victor N. Fondoh, Richard M. Awasom, Charles N. Edith, Pefoule L. Ntungwen, Winlove A. Roland, Bong Enow-Tanjong, Rebeca Njukeng, Patrick Shang, Judith Egbengu, Egbe P. Maruta, Talkmore Etheline, Akazong Leke, Robert Leo, Ayuk Nsame, Denis
Subject — haematological reference intervals; African population; pathogenic infections; haematological abnormalities; Cameroon; Clinical and Laboratory Standard Institute; local reference values; Bamenda
Description Background: In the era of evidence-based medicine, haematological reference intervals are essential for the interpretation of data for clinical decision-making, monitoring of treatment and research. It is not uncommon that reference intervals used in most African countries have been obtained from published scientific literature, textbooks, reagent/instrument manuals.Objective: The aim of this study was to determine haematological reference intervals of healthy adults in Bamenda, Cameroon.Methods: This was a cross-sectional study conducted between June and November 2015. Participants were voluntary blood donors at the Blood Bank Service of the Regional Hospital Bamenda aged between 18 and 65 years. The mean, median and standard deviation of the mean were calculated for each haematological parameter. The 95th percentile reference intervals were determined using the 2.5th and 97.5th percentile. The differences between gender for all the parameters were evaluated using the Kruskal-Wallis test. Significance was determined at the 95% confidence level.Results: Out of a total of 340 participants, 202 (59.4%) were men and 138 (40.6%) were women. The median red blood cell, haemoglobin, haematocrit and mean cell haemoglobin concentration were significantly higher in men than women (p 0.001). The median white blood cell, absolute lymphocytes count, absolute granulocytes and platelet counts for men were significantly lower than those for women (p 0.011).Conclusion: We propose that the present established haematological reference intervals in this study should be used for clinical management of patients and interpretation of laboratory data for research in Bamenda.
Publisher AOSIS
Date 2020-12-21
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ajlm.v9i1.1193
Source African Journal of Laboratory Medicine; Vol 9, No 1 (2020); 8 pages 2225-2010 2225-2002
Language eng
Relation https://ajlmonline.org/index.php/ajlm/article/view/1193/1836 https://ajlmonline.org/index.php/ajlm/article/view/1193/1835 https://ajlmonline.org/index.php/ajlm/article/view/1193/1837 https://ajlmonline.org/index.php/ajlm/article/view/1193/1834
Coverage — — —
Rights Copyright (c) 2020 Victor N. Fondoh, Richard M. Fondoh, Charles N. Awasom, Pefoule L. Edith, Winlove A. Ntungwen, Bong Roland, Rebeca Enow-Tanjong, Patrick Njukeng, Judith Shang, Egbe P. Egbengu, Talkmore Maruta, Akazong Etheline, Robert Leke, Ayuk Leo, Denis Nsame https://creativecommons.org/licenses/by/4.0