Confirmatory factor analysis of the Patient Health Questionnaire-9: A study amongst tuberculosis patients in the Free State province

Southern African Journal of Infectious Diseases

 
 
Field Value
 
Title Confirmatory factor analysis of the Patient Health Questionnaire-9: A study amongst tuberculosis patients in the Free State province
 
Creator Kigozi, Gladys
 
Subject — tuberculosis; depression; PHQ-9; construct validity; confirmatory factor analysis.
Description Background: There is growing evidence that depression is frequently comorbid with tuberculosis (TB) and is often associated with a decreased quality of life and poor treatment outcomes. The Patient Health Questionnaire (PHQ-9) is widely used to screen for depression in clinical settings in low-and middle-income countries. This study examined the construct validity and reliability of an interviewer-administered PHQ-9 in a sample of new TB patients in the Free State province of South Africa.Methods: A pilot study was conducted in 2019 amongst 208 new adult TB patients attending primary healthcare facilities in the Lejweleputswa District in the Free State. Trained fieldworkers administered a structured questionnaire comprising of questions on patient’s socio-demographic characteristics and the nine-item PHQ-9 to the patients. Confirmatory factor analysis and Cronbach’s alpha were respectively used to investigate the construct validity and internal consistency of the PHQ-9.Results: The model was a good fit, with a Tucker–Lewis index of 0.976, a comparative fit index of 0.982 and a root mean square error of approximation of 0.062 (90% CI: 0.032–0.089). All indicators showed significant positive factor loadings, with standardised coefficients ranging from 0.467 to 0.799. The PHQ-9 was characterised by a single factor latent structure – depression – underlying all items. The Cronbach’s alpha of the scale was 0.84.Conclusion: The results support a unidimensional structure of the PHQ-9, with satisfactory internal consistency implying that the scale is valid and reliable. The TB programme can confidently consider the PHQ-9 for the routine assessment of depression amongst TB patients in the Free State province and similar settings.
 
Publisher AOSIS Publishing
 
Contributor
Date 2020-12-21
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajid.v35i1.242
 
Source Southern African Journal of Infectious Diseases; Vol 35, No 1 (2020); 6 pages 2313-1810 2312-0053
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajid.co.za/index.php/sajid/article/view/242/486 https://sajid.co.za/index.php/sajid/article/view/242/485 https://sajid.co.za/index.php/sajid/article/view/242/487 https://sajid.co.za/index.php/sajid/article/view/242/484
 
Coverage — — —
Rights Copyright (c) 2020 Gladys Kigozi https://creativecommons.org/licenses/by/4.0
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