Paediatric atopic eczema (atopic dermatitis) in South Africa: A practical algorithm for the management of mild-to-moderate disease in daily clinical practice

South African Family Practice

 
 
Field Value
 
Title Paediatric atopic eczema (atopic dermatitis) in South Africa: A practical algorithm for the management of mild-to-moderate disease in daily clinical practice
 
Creator Kannenberg, Susanna M. Karabus, Sarah Visser, Willem I. Aboobaker, Jamilabibi Kriel, Magdalena M. Levin, Michael Magigaba, Basil Manjra, Ahmed Misra, Rupesh Mpofu, Pholile Tshigabe, Azwitamisi Luger, Thomas
 
Subject — atopic dermatitis; atopic eczema; treatment algorithm; pimecrolimus; tacrolimus
Description Background: Atopic eczema (AE) is a chronic, highly pruritic, inflammatory skin condition with increasing prevalence worldwide. Atopic eczema mostly affects children, impairing quality of life with poor disease control leading to progression of other atopic disorders. As most patients in South Africa have no access to specialist healthcare, a practical approach is needed for the management of mild-to-moderate AE in paediatric patients for daily clinical practice.Methods: A panel of experts in AE convened to develop a practical algorithm for the management of AE for children and adolescents in South Africa.Results: Regular moisturising with an oil-based emollient remains the mainstay of AE treatment. Severe AE flares should be managed with topical corticosteroids (TCSs). For mild-to-moderate AE flares in sensitive skin areas, a topical calcineurin inhibitor (TCI) should be applied twice daily from the first signs of AE until complete resolution. Topical corticosteroids may be used when TCIs are unavailable. In non-sensitive skin areas, TCSs should be used for mild-to-moderate AE, but TCIs twice daily may be considered. Proactive maintenance treatment with low-dose TCI or TCS 2–3 times weekly and the liberal use of emollients is recommended for patients with recurrent flares.Conclusions: This algorithm aims to simplify treatment of paediatric AE, optimising clinical outcomes and reducing disease burden. This approach excludes treatment of patients with severe AE, who should be referred to specialist care. Emphasis has been given to the importance of general skincare, patient education and the topical anti-inflammatory medications available in South Africa (TCSs and TCIs).
 
Publisher AOSIS
 
Contributor Medical writing assistance in the preparation of this manuscript was provided by Jane Murphy and Alex Bowen (both of CircleScience, an Ashfield Company, part of UDG Healthcare plc), and funded by Meda, a Mylan company.
Date 2020-11-23
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article —
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/safp.v62i1.5190
 
Source South African Family Practice; Vol 62, No 1 (2020): Part 4; 9 pages 2078-6204 2078-6190
 
Language eng
 
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https://safpj.co.za/index.php/safpj/article/view/5190/6476 https://safpj.co.za/index.php/safpj/article/view/5190/6474 https://safpj.co.za/index.php/safpj/article/view/5190/6475 https://safpj.co.za/index.php/safpj/article/view/5190/6473
 
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Rights Copyright (c) 2020 Susanna M. Kannenberg, Sarah Karabus, Willem I. Visser, Jamilabibi Aboobaker, Magdalena M. Kriel, Michael Levin, Basil Magigaba, Ahmed Manjra, Rupesh Misra, Pholile Mpofu, Azwitamisi Tshigabe, Thomas Luger https://creativecommons.org/licenses/by/4.0
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