The fructose–copper connection: Added sugars induce fatty liver and insulin resistance via copper deficiency
Journal of Metabolic Health (previously Journal of Insulin Resistance)
| Field | Value | |
| Title | The fructose–copper connection: Added sugars induce fatty liver and insulin resistance via copper deficiency | |
| Creator | DiNicolantonio, James J. Mangan, Dennis O'Keefe, James H. | |
| Description | Background: Evidence suggests that the overconsumption of added sugars can induce fatty liver disease and insulin resistance.Aim: To propose a hypothesis that added sugars induce copper deficiency which can lead to hepatic iron overload, fatty liver disease, insulin resistance and eventually non-alcoholic steatohepatitis.Setting: On average, the intake of added sugars in humans is higher than levels that have been found to impair copper status in animals.Methods: Narrative review.Results: Fructose-induced copper deficiency may be a leading cause of fatty liver disease and insulin resistance.Conclusion: The reduction in the intake of added sugars may improve copper status and reduce the risk of fatty liver disease and insulin resistance. | |
| Publisher | AOSIS | |
| Date | 2018-09-26 | |
| Identifier | 10.4102/jir.v3i1.43 | |
| Source | Journal of Insulin Resistance; Vol 3, No 1 (2018); 3 pages 2519-7533 2412-2785 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://insulinresistance.org/index.php/jir/article/view/43/142
https://insulinresistance.org/index.php/jir/article/view/43/140
https://insulinresistance.org/index.php/jir/article/view/43/141
https://insulinresistance.org/index.php/jir/article/view/43/139
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