Type 2 diabetes mellitus, physical activity, yoga and telomere length: A literature review

Journal of Insulin Resistance

Field Value
Title Type 2 diabetes mellitus, physical activity, yoga and telomere length: A literature review
Creator Ughreja, Reepa A. Ughreja, Reena A.
Subject — Type 2 Diabetes Mellitus; Yoga; Physical Activity; Telomere Length; Quality of Life
Description Background: Type 2 diabetes mellitus (DM), a chronic metabolic disease prevalent in adults, is also prevalent amongst children, adolescents and young adults. On understanding the molecular basis of diabetes, a significant association is found between telomere length (TL) and type 2 DM.Aim: The aim of the study was to review the available evidence on effect of physical activity and yoga on DM including their effect on TL.Setting: The study was conducted in Bangalore.Method: A number of databases such as Google Scholar, PubMed and Cochrane Review were searched for relevant articles using keywords such as ’diabetes’, ‘type 2 DM’, ‘physical activity’, ‘yoga’, ‘TL’ and ‘telomerase activity’. All types of articles were included for the study, such as randomised controlled trial, systematic reviews, literature review and pilot study. Non-English articles were excluded from the study.Results: Studies have demonstrated the effectiveness of yoga and physical exercise in type 2 DM in various ways, such as reducing fasting blood glucose and glycosylated haemoglobin; improving lipid profile, blood pressure and waist-to-hip ratio; reducing inflammatory, oxidative and psychological stress markers; and improving the quality of life of patients. However, limited information is available on the effect of these interventions on TL in type 2 DM and mechanisms involved.Conclusion: Recent studies have shown positive effects of yoga and physical activity on TL. However, there is a dearth of good-quality studies evaluating the effects of yoga on TL in type 2 DM. Future studies need to be conducted with standard treatment protocols, long-term follow-up, appropriate control groups and large sample size.
Publisher AOSIS
Date 2019-09-10
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/jir.v4i1.52
Source Journal of Insulin Resistance; Vol 4, No 1 (2019); 9 pages 2519-7533 2412-2785
Language eng
Relation https://insulinresistance.org/index.php/jir/article/view/52/194 https://insulinresistance.org/index.php/jir/article/view/52/193 https://insulinresistance.org/index.php/jir/article/view/52/195 https://insulinresistance.org/index.php/jir/article/view/52/192
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Rights Copyright (c) 2019 Reepa A. Ughreja, Reena A. Ughreja https://creativecommons.org/licenses/by/4.0