Antipsychotic medication non-adherence among schizophrenia patients in Central Ethiopia
South African Journal of Psychiatry
| Field | Value | |
| Title | Antipsychotic medication non-adherence among schizophrenia patients in Central Ethiopia | |
| Creator | Tareke, Minale Tesfaye, Siranesh Amare, Desalegn Belete, Tilahun Abate, Andargie | |
| Description | Background: Despite the fact that adherence to antipsychotic medications is the cornerstone in the treatment and prevention of relapse of the disease, non-adherence is a major problem among schizophrenia patients. The purpose of this study was to assess the magnitude and factors associated with antipsychotic medication non-adherence among schizophrenia patients in Amanuel Mental Specialized Hospital.Method: An institution-based cross-sectional study was conducted among 412 people with schizophrenia at Amanuel Mental Specialized Hospital from April to May 2014. Non-adherence was assessed using the questionnaire of Morisky medication adherence rating scale and semi-structured questions for assessment of associated factors. Logistic regression analysis was used to assess predictors of non-adherence.Results: Prevalence of non-adherence was 41.0% among schizophrenia patients. Living in rural areas (adjusted odds ratio [AOR] = 2.07; 95% confidence interval [CI]: 1.31, 3.28), current substance use (AOR = 1.67; 95% CI: 1.09, 2.56), long duration of treatment (AOR = 2.07; 95% CI: 1.22, 3.50) and polypharmacy (AOR = 2.13; 95% CI: 1.34, 3.40) were found to be significantly associated with non-adherence.Conclusion: The results indicate that non-adherence to antipsychotic medication was a major problem among patients with schizophrenia. Reducing the number of antipsychotic medications and availing drugs in rural areas may decrease the level of non-adherence. | |
| Publisher | AOSIS | |
| Date | 2018-03-05 | |
| Identifier | 10.4102/sajpsychiatry.v24i0.1124 | |
| Source | South African Journal of Psychiatry; Vol 24 (2018); 6 pages 2078-6786 1608-9685 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajp.org.za/index.php/sajp/article/view/1124/975
https://sajp.org.za/index.php/sajp/article/view/1124/972
https://sajp.org.za/index.php/sajp/article/view/1124/974
https://sajp.org.za/index.php/sajp/article/view/1124/971
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