Antipsychotic medication non-adherence among schizophrenia patients in Central Ethiopia

South African Journal of Psychiatry


 
 
Field Value
 
Title Antipsychotic medication non-adherence among schizophrenia patients in Central Ethiopia
 
Creator Tareke, Minale Tesfaye, Siranesh Amare, Desalegn Belete, Tilahun Abate, Andargie
 
Subject — Schizophrenia; Antipsychotics; Non adherence
Description Background: Despite the fact that adherence to antipsychotic medications is the cornerstone in the treatment and prevention of relapse of the disease, non-adherence is a major problem among schizophrenia patients. The purpose of this study was to assess the magnitude and factors associated with antipsychotic medication non-adherence among schizophrenia patients in Amanuel Mental Specialized Hospital.Method: An institution-based cross-sectional study was conducted among 412 people with schizophrenia at Amanuel Mental Specialized Hospital from April to May 2014. Non-adherence was assessed using the questionnaire of Morisky medication adherence rating scale and semi-structured questions for assessment of associated factors. Logistic regression analysis was used to assess predictors of non-adherence.Results: Prevalence of non-adherence was 41.0% among schizophrenia patients. Living in rural areas (adjusted odds ratio [AOR] = 2.07; 95% confidence interval [CI]: 1.31, 3.28), current substance use (AOR = 1.67; 95% CI: 1.09, 2.56), long duration of treatment (AOR = 2.07; 95% CI: 1.22, 3.50) and polypharmacy (AOR = 2.13; 95% CI: 1.34, 3.40) were found to be significantly associated with non-adherence.Conclusion: The results indicate that non-adherence to antipsychotic medication was a major problem among patients with schizophrenia. Reducing the number of antipsychotic medications and availing drugs in rural areas may decrease the level of non-adherence.
 
Publisher AOSIS
 
Contributor
Date 2018-03-05
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip application/xml application/pdf
Identifier 10.4102/sajpsychiatry.v24i0.1124
 
Source South African Journal of Psychiatry; Vol 24 (2018); 6 pages 2078-6786 1608-9685
 
Language eng
 
Relation https://sajp.org.za/index.php/sajp/article/view/1124/975 https://sajp.org.za/index.php/sajp/article/view/1124/972 https://sajp.org.za/index.php/sajp/article/view/1124/974 https://sajp.org.za/index.php/sajp/article/view/1124/971
 
Coverage — — —
Rights https://creativecommons.org/licenses/by/4.0