The use of cyproterone acetate in a forensic psychiatric cohort of male sex offenders and its associations with sexual activity and sexual functioning

South African Journal of Psychiatry

 
 
Field Value
 
Title The use of cyproterone acetate in a forensic psychiatric cohort of male sex offenders and its associations with sexual activity and sexual functioning
 
Creator Lippi, Gian van Staden, Paul J.
 
Subject Psychiatry Cyproterone acetate; sexual activity; sexual functioning
Description Background: Cyproterone acetate (CPA) is a steroidal anti-androgenic medication used in the field of psychiatry for the treatment of paraphilic disorders, hypersexuality, and inappropriate sexual behaviour which may be present in patients with disorders such as mild and major neurocognitive disorders. In the forensic psychiatric population, it is prescribed for these indications especially for patients with a history of committing a sexual offence or who are at moderate to high risk of recidivism.Objectives: To investigate the use of CPA in a forensic psychiatric cohort of male sex offenders and its associations with sexual activity and sexual functioning.Methods: Seventy-six forensic psychiatric patients from Weskoppies Hospital in Pretoria, South Africa, participated in the study which measured their sexual functioning. A specifically designed questionnaire was used to capture relevant background information. The use of CPA was studied. The Changes in Sexual Functioning Questionnaire, Male Clinical Version (CSFQ-M-C) was used to measure sexual functioning of participants. The CSFQ-M-C scores, and those of all its subscales, of participants on CPA were compared to those not on the drug. Relevant statistical analyses were performed.Results: Thirteen out of the 76 participants were being treated with CPA (17.11%). In total, 53.85% of the participants on CPA and 65.08% not on CPA had scores indicating the presence of sexual dysfunction. The total CSFQ-M-C scores for participants on CPA (mean = 40.54; median = 42) were not statistically significantly lower than those not on the drug (mean = 41.22; median = 41). More notable is that the use of CPA in this population was associated with lower levels of desire, frequency of and pleasure from sexual activity. There was an association between having intellectual disability and being treated with CPA.Conclusion: That all the participants were being treated with psychotropic medication could account for the high percentage of sexual dysfunction in any or all areas of sexual functioning and contribute to the small difference in CSFQ-M-C scores between the two groups. Only a tentative conclusion can be made that CPA may be more effective in decreasing levels of desire, frequency and pleasure related to sexual activity than other areas of sexual functioning. The indication for the use of CPA in this population should be assessed clinically according to patient circumstances and risk assessment.
 
Publisher AOSIS
 
Contributor
Date 2017-03-10
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Cross sectional; naturalistic; quantitative
Format text/html application/epub+zip application/xml application/pdf
Identifier 10.4102/sajpsychiatry.v23i0.982
 
Source South African Journal of Psychiatry; Vol 23 (2017); 8 pages 2078-6786 1608-9685
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajp.org.za/index.php/sajp/article/view/982/795 https://sajp.org.za/index.php/sajp/article/view/982/794 https://sajp.org.za/index.php/sajp/article/view/982/796 https://sajp.org.za/index.php/sajp/article/view/982/788
 
Coverage Pretoria, South Africa Current Male; State Patients
Rights Copyright (c) 2017 Gian Lippi, Paul J. van Staden https://creativecommons.org/licenses/by/4.0
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