Does adjunctive use of metronidazole plus amoxicillin benefit patients receiving non-surgical scaling and root planing for the treatment of generalised aggressive periodontitis?
Open Journal of Implant Dentistry
Field | Value | |
Title | Does adjunctive use of metronidazole plus amoxicillin benefit patients receiving non-surgical scaling and root planing for the treatment of generalised aggressive periodontitis? | |
Creator | van Zyl, Andre W. Hartshorne, Johan Carrasco-Labra, Alonso | |
Description | This article describes a double-blinded, placebo-controlled randomised clinical trial thatinvolved 30 eligible subjects experiencing generalised aggressive periodontitis. Subjectswere randomly assigned to either the test group (scaling and root planing + metronidazole[400 mg]) and amoxicillin [500 mg]) or the control group (scaling and root planing withoutthe adjunctive antibiotics combination). Both antibiotics and placebos were administeredthree times per day for 14 days. Participants were examined at baseline, and again six monthsand one year after therapy. Both therapies led to a statistically significant improvementin all clinical parameters as measured after one year. However, subjects who received themetronidazole–amoxicillin combination showed the greatest reduction in mean probingdepth, an improved clinical attachment level and a lower mean number of residual sitesafter one year. The investigators concluded that the non-surgical treatment of generalisedaggressive periodontitis was markedly improved by the adjunctive use of metronidazole andamoxicillin up to one year after treatment. | |
Publisher | AOSIS | |
Date | 2013-03-26 | |
Identifier | 10.4102/ojid.v1i1.7 | |
Source | Open Journal of Implant Dentistry; Vol 1, No 1 (2013); 3 pages 2226-4507 n/a | |
Language | eng | |
Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://ojid.org/index.php/ojid/article/view/7/18
https://ojid.org/index.php/ojid/article/view/7/19
https://ojid.org/index.php/ojid/article/view/7/20
https://ojid.org/index.php/ojid/article/view/7/17
|
|
ADVERTISEMENT