Cutaneous tuberculosis in HIV-infected individuals: Lessons learnt from a case series
Southern African Journal of HIV Medicine
| Field | Value | |
| Title | Cutaneous tuberculosis in HIV-infected individuals: Lessons learnt from a case series | |
| Creator | Tshisevhe, Vhudzani Mbelle, Nontombi Peters, Remco P.H. | |
| Description | Introduction: Extrapulmonary tuberculosis (TB) causes a significant burden of disease worldwide, especially among HIV-infected individuals and those with other immunosuppressive conditions. Cutaneous TB is an important manifestation of extrapulmonary TB but is uncommonly reported in South Africa despite the high burden of HIV and TB co-infection. There is a paucity of published data on clinical presentation and outcome of cutaneous TB in this context. Raising awareness of this condition among clinicians is imperative to improve early diagnosis and optimise treatment outcomes.Patient presentation: In this series, we present three cases of cutaneous TB, two adults and one child, referred to a tertiary hospital from two primary healthcare centres and from a general practitioner. We demonstrate that the clinical presentation is diverse, ranging from papular lesions to abscesses, and that concordant pulmonary TB may be present.Management: In particular, we show the importance of performing diagnostic procedures (e.g. aspiration) in individuals presenting with an abscess that does not respond to broad spectrum antimicrobial treatment, particularly in those with advanced immunosuppression.Outcome and conclusion: The outcome of our three patients was poor, highlighting the need for earlier diagnosis in this WHO Stage 4 condition and intensive management of clinical cases.Keywords: HIV-medicine; Retro-Viral Disease; Mycobacteria; Tuberculosis; Multidrug Resistance; Cutaneous Tuberculosis; Cutaneous Disease; immunocompromised. | |
| Publisher | AOSIS | |
| Date | 2019-03-12 | |
| Identifier | 10.4102/sajhivmed.v20i1.895 | |
| Source | Southern African Journal of HIV Medicine; Vol 20, No 1 (2019); 3 pages 2078-6751 1608-9693 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajhivmed.org.za/index.php/hivmed/article/view/895/1336
https://sajhivmed.org.za/index.php/hivmed/article/view/895/1337
https://sajhivmed.org.za/index.php/hivmed/article/view/895/1338
https://sajhivmed.org.za/index.php/hivmed/article/view/895/1334
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