A case of a drug reaction to sulfasalazine in a patient infected with HIV
Southern African Journal of HIV Medicine
| Field | Value | |
| Title | A case of a drug reaction to sulfasalazine in a patient infected with HIV | |
| Creator | Swart, Leanne Schapkaitz, Elise Baiden, Anima | |
| Description | Introduction: The diagnosis of drug reaction with eosinophilia and systemic symptoms (DRESS) in human immunodeficiency virus (HIV) patients on multiple drugs with concomitant disorders presents a diagnostic challenge.Patient presentation: We describe a case of a drug reaction to sulfasalazine in a 46 year old HIV-infected female with concurrent rheumatoid arthritis which presented atypically with a marked peripheral blood plasmacytosis mimicking a lymphoproliferative neoplasm.Management and outcome: A diagnosis of DRESS was made in conjunction with the laboratory and clinical presenting findings. Sulfasalazine was immediately discontinued. The mucocutaneous rash and systemic symptoms (which included fever, lymphadenopathy and multi-organ dysfunction) resolved with supportive treatment. This included topical and systemic corticosteroids.Conclusion: In conclusion, it is important to consider drug reactions when evaluating patients infected with HIV. | |
| Publisher | AOSIS | |
| Date | 2018-12-03 | |
| Identifier | 10.4102/sajhivmed.v19i1.829 | |
| Source | Southern African Journal of HIV Medicine; Vol 19, No 1 (2018); 3 pages 2078-6751 1608-9693 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajhivmed.org.za/index.php/hivmed/article/view/829/1288
https://sajhivmed.org.za/index.php/hivmed/article/view/829/1287
https://sajhivmed.org.za/index.php/hivmed/article/view/829/1289
https://sajhivmed.org.za/index.php/hivmed/article/view/829/1270
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