Late stage presentation of HIV-positive patients to antiretroviral outpatient clinic in Zambia

Southern African Journal of HIV Medicine

 
 
Field Value
 
Title Late stage presentation of HIV-positive patients to antiretroviral outpatient clinic in Zambia
 
Creator Martin, Timothy Mweene, Morgan
 
Subject Medicine; infectious diseases; HIV medicine HIV; AIDS; cART; combination antiretroviral therapy; clinical audit; WHO cART guidelines; Zambian ministry of health cART guidelines
Description Background: The World Health Organization (WHO) and the Zambian Ministry of Health set out new guidelines on combination antiretroviral therapy (cART) in 2013 expanding the eligibility criteria for patients with HIV.Objectives: The primary objective were to determine when cART was initiated in HIV-positive outpatients according to clinical and immunological criteria, and to identify what proportion of patients who were eligible for cART according to 2013 WHO and 2013 Zambian cART guidelines were currently on cART.Methodology: This was a clinical audit of HIV-positive outpatients attending the cART clinic at Ndola Central Hospital in Ndola, Zambia, with retrospective cross-sectional chart review and survey design. Data were collected from clinical records and interviews with patients.Results: A total of 99% of patients eligible for cART according to 2013 guidelines were on treatment. Clinical staging of patients at initiated on cART (n = 206) was as follows: 28% clinical stage I, 21% clinical stage II, 36% clinical stage III and 15% clinical stage IV. The median CD4 count when patients were started on cART was 147 cells/mm3 .Conclusion: The results show that a majority of patients were initiated on cART late in their disease course according to immunological (CD4 200 cell/mm3 ) and clinical criteria (stage III or IV). However, the vast majority of patients eligible for cART were currently on treatment. The late initiation of cART appears to be a result of late diagnosis of HIV.
 
Publisher AOSIS
 
Contributor
Date 2017-11-30
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Clinical audit; descriptive study
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajhivmed.v18i1.717
 
Source Southern African Journal of HIV Medicine; Vol 18, No 1 (2017); 8 pages 2078-6751 1608-9693
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajhivmed.org.za/index.php/hivmed/article/view/717/1052 https://sajhivmed.org.za/index.php/hivmed/article/view/717/1051 https://sajhivmed.org.za/index.php/hivmed/article/view/717/1053 https://sajhivmed.org.za/index.php/hivmed/article/view/717/1048
 
Coverage Sub-Saharan Africa; Southern Africa; Zambia; Ndola; Ndola Central Hospital 2014 HIV positive; Adults; Black African; Zambian
Rights Copyright (c) 2017 Timothy Martin, Morgan Mweene https://creativecommons.org/licenses/by/4.0
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