Pulmonary impairment after tuberculosis in a South African population
South African Journal of Physiotherapy
| Field | Value | |
| Title | Pulmonary impairment after tuberculosis in a South African population | |
| Creator | Cole, Gibwa Miller, Duncan Ebrahim, Tasneem Dreyden, Tannith Simpson, Rory Manie, Shamila | |
| Description | Background: In South Africa, pulmonary tuberculosis (PTB) remains a problem of epidemic proportions. Despite evidence demonstrating persistent lung impairment after PTB cure, few population-based South African studies have investigated this finding. Pulmonary rehabilitation post-cure is not routinely received.Objectives: To determine the effects of PTB on lung function in adults with current or past PTB. To determine any association between PTB and chronic obstructive pulmonary disease (COPD). Methods: This study was observational and cross-sectional in design. Participants (n = 55) were included if they were HIV positive on treatment, had current PTB and were on treatment, and/or had previous PTB and completed treatment or if they were healthy adult subjects with no history of PTB. A sample of convenience was used with participants coming from a similar socio-economic background and undergoing spirometry testing. Multiple regression analyses were conducted on each lung function variable.Results: Compared to normal percentage-predicted values, forced expiratory volume in 1 second (FEV1 ), forced vital capacity (FVC) and FEV1 :FVC were significantly reduced in those with current PTB by 23.39%, 15.99% and 6.4%, respectively. Both FEV1 and FVC were significantly reduced in those with past PTB by 11.76% and 10.79%, respectively. There was no association between PTB and COPD – those with previous PTB having a reduced FEV1 :FVC (4.88% less than the norm), which was just short of significance (p = 0.059).Conclusions: Lung function is reduced both during and after treatment for PTB and these deficits may persist. This has implications regarding the need for pulmonary rehabilitation even after medical cure.Keywords: Lung function, pulmonary, tuberculosis | |
| Publisher | AOSIS | |
| Date | 2016-06-30 | |
| Identifier | 10.4102/sajp.v72i1.307 | |
| Source | South African Journal of Physiotherapy; Vol 72, No 1 (2016); 6 pages 2410-8219 0379-6175 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajp.co.za/index.php/sajp/article/view/307/362
https://sajp.co.za/index.php/sajp/article/view/307/363
https://sajp.co.za/index.php/sajp/article/view/307/364
https://sajp.co.za/index.php/sajp/article/view/307/348
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