The radiological appearance of intracranial aneurysms in adults infected with the human immunodeficiency virus (HIV)

SA Journal of Radiology

 
 
Field Value
 
Title The radiological appearance of intracranial aneurysms in adults infected with the human immunodeficiency virus (HIV)
 
Creator Blignaut, Gerrit Loggenberg, Eugene de Vries, Coert
 
Subject Radiology HIV; intracranial; aneurysm; radiological appearance; adults
Description Background: The global prevalence of intracranial aneurysms is estimated at 2.3%. Limited literature is available on intracranial aneurysms in HIV-infected patients.Objectives: To describe the radiological appearance of intracranial aneurysms in HIV-positive adults.Method: In this retrospective analysis of data, 23 HIV-positive patients, of which 15 (65.2%)were female, with a total of 41 aneurysms were included. The mean age was 38 years, and their median CD4 count was 305 x 106/L. Inclusion criteria comprised subarachnoid haemorrhage and confirmed intracranial aneurysms on four-vessel angiography.Results: Fifteen (65.2%) patients had a single aneurysm, of which 12 (80.0%) had a saccular appearance. Seven (46.7%) of the single aneurysms had a neck width larger than 50% of the transverse aneurysm sac size. The mean longitudinal diameter of the aneurysm sac was 4.9 mm and the transverse diameter 4.4 mm. More than half of these aneurysms occurred at the anterior communicating artery. The median CD4 count of single-aneurysm patients was 319 x 106 /L. Eight patients (34.8%) had multiple aneurysms, with a total of 26 aneurysms (range 2–6 aneurysms per patient), of which 13 (50.0%) had a complex appearance. Twenty-four (92.3%) of the multiple aneurysms had a neck width larger than 50% of the transverse aneurysm sac size. The mean longitudinal diameter of the aneurysm sac was 4.0 mm and the transverse diameter 3.9 mm. The multiple aneurysms occurred more commonly in the internal carotid artery. These patients had a median CD4 count of 294 x 106/L.Conclusion: HIV-associated intracranial aneurysms occur at a younger age, appear to be saccular and complex in shape, with a wide neck, and might rupture at small sizes.
 
Publisher AOSIS
 
Contributor
Date 2014-04-04
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Retrospective analysis
Format text/html application/octet-stream text/xml application/pdf
Identifier 10.4102/sajr.v18i1.586
 
Source South African Journal of Radiology; Vol 18, No 1 (2014); 4 pages 2078-6778 1027-202X
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajr.org.za/index.php/sajr/article/view/586/722 https://sajr.org.za/index.php/sajr/article/view/586/723 https://sajr.org.za/index.php/sajr/article/view/586/724 https://sajr.org.za/index.php/sajr/article/view/586/720
 
Coverage — — HIV positive adults with intracranial aneurysms
Rights Copyright (c) 2014 Gerrit Blignaut, Eugene Loggenberg, Coert de Vries https://creativecommons.org/licenses/by/4.0
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