Macular thicknesses in patients with keratoconus: An optical coherence tomography study

African Vision and Eye Health

 
 
Field Value
 
Title Macular thicknesses in patients with keratoconus: An optical coherence tomography study
 
Creator Deonarain, Sohani Motala, Azeezah Mthembu, Talent Nxele, Nomfundo Phakathi, Thabiso Thwala, Nonkululeko Rampersad, Nishanee
 
Subject Optometry; ophthalmology macular thickness; keratoconus; optical coherence tomography; corneal ectasia; parafoveal; peripheral retinal thickness.
Description Background: Keratoconus, a corneal ectasia associated with thickness and structural changes, has been reported to co-exist with posterior segment ocular conditions. However, very few studies have reported on macular thicknesses in individuals with keratoconus.Aim: The aim of this study was to investigate macular thicknesses in participants with keratoconus.Setting: This study was conducted at the University of KwaZulu-Natal (UKZN).Methods: A comparative cross-sectional research design was used. The sample consisted of 88 participants with 44 each in the control and keratoconus (15, 11 and 18 with mild, moderate and severe keratoconus, respectively) groups. Macular thicknesses were obtained with the Fourier-domain Optovue iVue100 optical coherence tomographer using the nine Early Treatment Diabetic Retinopathy Study sectors. Data were analysed using descriptive and inferential statistics.Results: Overall, the mean macular thicknesses were comparable among the control and three keratoconus groups (p ≥ 0.199). The mean central foveal thickness was greater in the severe keratoconus group (259 µm) than the other three study groups that showed similar measurements (247 µm – 248 µm). The central fovea was thinnest followed by the perifovea and parafovea in all four study groups. The mean thickness in the nasal and temporal quadrants of the parafovea and perifovea was thickest and thinnest, respectively, in all four study groups.Conclusion: Macular thicknesses via optical coherence tomography in individuals with keratoconus and controls are similar with thickness differences that are clinically insignificant. Consequently, macular thicknesses should be included in the preoperative assessment of individuals with keratoconus awaiting corneal transplantation to assess the integrity of the retina prior to surgery.
 
Publisher AOSIS
 
Contributor
Date 2019-09-25
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Cross-sectional comparative
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/aveh.v78i1.482
 
Source African Vision and Eye Health; Vol 78, No 1 (2019); 8 pages 2410-1516 2413-3183
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://avehjournal.org/index.php/aveh/article/view/482/1048 https://avehjournal.org/index.php/aveh/article/view/482/1047 https://avehjournal.org/index.php/aveh/article/view/482/1049 https://avehjournal.org/index.php/aveh/article/view/482/1046
 
Coverage South Africa — Young adults; keratoconus patients
Rights Copyright (c) 2019 Sohani Deonarain, Azeezah Motala, Thalent Mthembu, Nomfundo Nxele, Thabiso Phakathi, Nonkululeko Gcabashe, Nishanee Rampersad https://creativecommons.org/licenses/by/4.0
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